Publications by authors named "Chuangchang Wang"
Article Synopsis
- Elevated levels of soluble stimulating factor 2 (sST2) are linked to negative outcomes in cardiovascular diseases, particularly heart failure and acute coronary syndrome, but its association with hypertensive heart disease needed further exploration.
- This study involved analyzing sST2 levels and echocardiographic data from 483 patients to investigate its relationship with left ventricular hypertrophy (LVH) and geometric remodeling in essential hypertension (EH).
- The results indicated that higher sST2 levels were significantly associated with an increased risk of LVH and concentric hypertrophy, making sST2 a promising biomarker for diagnosing and assessing risks related to hypertensive heart disease.
Article Synopsis
- Left ventricular hypertrophy (LVH) is a condition related to high blood pressure that increases the risk of serious heart issues and is influenced by factors like gender, age, and kidney function.
- A study involving 417 patients with hypertension developed a risk assessment model using clinical characteristics and biomarker data.
- The model combining both types of data (clinical and biomarkers) was the most effective, highlighting significant risk factors such as being female, overweight/obese, longer duration of hypertension, and certain biomarker levels, while better kidney function offered some protection.
Atherosclerosis (AS) is a typical vascular disease. Emerging evidence has shown that circRNAs play key roles in the progression of AS, but the potential function and underlying mechanism of hsa_circ_0001879 remains unknown. We detected the expression level of hsa_circ_0001879 was determined by qRT-PCR, and the proliferation rate and migration ability of HUVECs were measured by CCK-8 assay and Transwell assay, respectively.
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