Publications by authors named "Chuang-Bo Xie"
Article Synopsis
- - Propofol, a common anesthetic, requires dosage adjustment based on aging, and researchers hypothesize that telomere length (TL) could help predict the appropriate dose needed, especially in elderly patients.
- - In a study involving 100 surgical patients, researchers analyzed the correlation between propofol dosage and factors such as TL, body weight, sex, and changes in the Bispectral Index (BIS) during anesthesia, finding a strong connection with TL (r = 0.78).
- - The study concluded that TL is a significant factor in predicting propofol dosage, which could enhance anesthesia safety and decrease complications, while mutations in the telomerase RNA component (TERC) were not detected. *
[Application of toll-like receptor agonists as an adjuvant component to malaria blood-stage vaccine].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
October 2011
Toll-like receptors (TLRs) belong to the category of pattern recognition receptor. The binding of TLRs with their respective ligands activates innate immune system, thereby initiates adaptive immune responses. As such, some TLR ligands or agonists have been used as an adjuvant component in a variety of vaccine formulations.
View Article and Find Full Text PDF