Background: Autologous costal cartilage has been used for augmentation rhinoplasty in Asia for many years. This study aimed to assess the effectiveness and safety of hybrid grafting of costal cartilage for dorsal augmentation, septal reconstruction, and tip augmentation for Asian patients.
Methods: A surgical technique was introduced and patients having rhinoplasty using this technique from April 2020 to March 2021 were retrospectively studied.
Objectives: To determine antimicrobial stewardship (AMS) programme practices in Asian secondary- and tertiary-care hospitals.
Methods: AMS programme team members within 349 hospitals from 10 countries (Cambodia, India, Indonesia, Japan, Malaysia, Pakistan, the Philippines, Taiwan, Thailand and Vietnam) completed a questionnaire via a web-based survey link. The survey contained questions as to whether 12 core components deemed essential for AMS programmes were implemented.
Microplastics (MPs), a class of emerging contaminants, are ubiquitous in the environment, but limited information is known about them in remote terrestrial environment at high-altitude areas with inconvenient traffic and sparsely populated. In this study, 54 soil samples were collected from various land use patterns (greenhouse, ordinary farmland, grassland, and bare land) in western area of the Tibetan Plateau to determine the influence of land use type, altitude, meteorological parameters, and distance from the road edge on MP distribution. The MP abundance ranged from 0 (not detected) to 190 items/kg, with an average number of 64.
View Article and Find Full Text PDFActa Biochim Biophys Sin (Shanghai)
August 2022
The skin is an organ that protects against injury and infection but can be damaged easily. Wound healing is a subtle balance which, if broken, can lead to keloid formation. Small noncoding (nc) RNAs can be of "housekeeping," for example, ribosomal RNAs and transfer RNAs, or "regulatory," for example, microRNAs (miRNAs or miRs), small nucleolar RNAs (snoRNAs), and P-element-induced Wimpy testis (PIWI)-interacting RNA (piRNA) types.
View Article and Find Full Text PDFBackground: Haploinsufficiency is widely accepted as the pathogenic mechanism of spastic paraplegia type 4 (SPG4). However, there are some cases that cannot be explained by reduced function of the spastin protein encoded by SPAST.
Objectives: To identify the causative gene of autosomal dominant hereditary spastic paraplegia in three large Chinese families and explore the pathological mechanism of a spastin variant.
Microplastics (MPs) have been widely detected in the environments, yet the sources of MPs in freshwater of remote areas at high altitude were not well understood. This study investigated the abundance and distribution of MPs in water bodies and sediments at the Qinghai-Tibet Plateau (QTP). MPs were detected in all samples (47 water and 33 sediment samples) with the mean abundance of 624.
View Article and Find Full Text PDFPotentially toxic elements (PTEs) generated from mining activities have affected ecological diversity and ecosystem functions around the world. Accurately assessing the long-term effects of PTEs is critical to classifying recoverable areas and proposing management strategies. Mining activities that shape geographical patterns of biodiversity in individual regions are increasingly understood, but the complex interactions on broad scales and in changing environments are still unclear.
View Article and Find Full Text PDFFour rutheniumethynyl-triarylamine complexes 1-4 with different aryl bridge cores were prepared. The solid structures of complexes 2-4 were fully confirmed by X-ray single-crystal diffraction analysis. Two consecutive one-electron oxidation processes of complexes 1-4 were attributed to the ruthenium and nitrogen centers, as revealed by cyclic voltammetry and square-wave voltammogram.
View Article and Find Full Text PDFExtensive research has focused on the response of vegetation to climate change, including potential mechanisms and resulting impacts. Although many studies have explored the relationship between vegetation and climate change in China, research on spatiotemporal distribution changes of climate regimes using natural vegetation as an indicator is still lacking. Further, limited information is available on the response of vegetation to shifts in China's regional climatic zones.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
October 2019
BACKGROUND The methylation status of RUNX3 promoter region, its impact on RUNX3 gene expression, and Th1/Th2 imbalance are unknown in bronchiolitis. This study aimed to explore the predictors of bronchiolitis developing into asthma. MATERIAL AND METHODS The methylation status of RUNX3 promoter was assessed using Illumina HiSeq platform method.
View Article and Find Full Text PDFInfect Control Hosp Epidemiol
October 2018
Inappropriate use of antibiotics is contributing to a serious antimicrobial resistance problem in Asian hospitals. Despite resource constraints in the region, all Asian hospitals should implement antimicrobial stewardship (AMS) programs to optimize antibiotic treatment, improve patient outcomes, and minimize antimicrobial resistance. This document describes a consensus statement from a panel of regional experts to help multidisciplinary AMS teams design programs that suit the needs and resources of their hospitals.
View Article and Find Full Text PDFBackground And Purpose: Vibrio vulnificus causes primary bacteremia and necrotizing wound infection, leading to high morbidity and mortality in humans. This study aimed to evaluate the antimicrobial effect of cefotaxime and minocycline on proinflammatory cytokine levels in a murine model of V. vulnificus infection.
View Article and Find Full Text PDFJ Microbiol Immunol Infect
February 2007
Background And Purpose: Little is known about the possible synergism of baicalein, a bioactive flavone of Scutellariae radix (a Chinese herb), when used in conjunction with other antimicrobial agents against vancomycin-resistant Enterococcus (VRE). This in vitro study examined the possible synergism of the combination of baicalein and gentamicin against VRE.
Methods: Minimal inhibitory concentrations (MICs) of baicalein as well as gentamicin were determined against 39 clinical isolates of VRE by the agar dilution method.
Biochem Biophys Res Commun
September 2004
Blue fluorescent protein, BfgV, found from Vibrio vulnificus CKM-1, fluoresces through augmenting the intrinsic fluorescence of bound NADPH. Random mutagenesis and DNA shuffling were applied to increase the fluorescent intensity of BfgV. The wild type bfgV gene was subjected to four cycles of mutagenesis processes.
View Article and Find Full Text PDFA blue fluorescent protein, BfgV, belonging to the short-chain dehydrogenase/reductase superfamily, was found in a non-bioluminescent pathogen Vibrio vulnificus CKM-1. This protein has fluorescence spectra with two excitation peaks at 283 and 352 nm, and one emission peak at 456 nm. BfgV fluoresces through effectively augmenting the intrinsic fluorescence of NADPH bound to it.
View Article and Find Full Text PDFThe gene (lipA) encoding the extracellular lipase and its downstream gene (lipB) from Vibrio vulnificus CKM-1 were cloned and sequenced. Nucleotide sequence analysis and alignments of amino acid sequences suggest that Lip Ais a member of bacterial lipase family I.1 and that LipB is a lipase activator of LipA.
View Article and Find Full Text PDFThe structural gene encoding the extracellular lipase of Aeromonas hydrophila MCC-2 was cloned and found to be expressed in Escherichia coli using its own promoter. When the cloned gene (lip) was expressed in E. coli minicells, an 80 kDa protein was identified.
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