Comparative transcriptome analysis identified genes involved in ovarian development in Takifugu rubripes.

Ovarian development is a complex process involving multiple genes, but the molecular mechanisms underlying this process in Takifugu rubripes remain poorly understood. This study aimed to identify genes associated with ovarian development in T. rubripes and to investigate the regulatory mechanisms of oocyte maturation.

Physiological responses to different temperature in the liver of Takifugu rubripes larvae revealed by integrated transcriptomic and metabolomic analyses.

Water temperature plays a vital role in shaping the physical conditions crucial for the growth, development and reproduction of fish species. Since limited comprehensive multi-omics analyses exploring the molecular mechanisms of temperature influences on the early life stages of fish. Here, the effects of temperature variations on the growth of Takifugu rubripes, a commercial teleost farmed in Asia were investigated.

Effects of temperature to the liver transcriptome in the hybrid puffer fish (Takifugu rubripes ♀ × Takifugu obscurus ♂).

Water temperature exerts a crucial impact on the growth and development of fish. Hybrids may integrate the superior traits of their parents, thereby leading to higher economic benefits. Takifugu rubripes and T.

AP001885.4 promotes the proliferation of esophageal squamous cell carcinoma cells by histone lactylation- and NF-κB (p65)-dependent transcription activation and METTL3-mediated mRNA stability of c-myc.

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignant neoplasm, and up to now, the role of long non-coding RNA (lncRNA) AP001885.4 in cancer, including ESCC, is absolutely unclear. The GEPIA database was applied to identify differentially expressed and prognosis-associated genes in esophageal cancer (ESCA).

Blocking SLC7A11 attenuates the proliferation of esophageal squamous cell carcinoma cells.

The role of ferroptosis-associated gene SLC7A11 in esophageal cancer progression is largely unknown, therefore, the effects of blocking SLC7A11 on esophageal squamous cell carcinoma (ESCC) cells are evaluated. Results showed that SLC7A11 was overexpressed in ESCC tissues both in mRNA and protein levels. Blocking SLC7A11 using Erastin suppressed the proliferation and colony formation of ESCC cells, decreased cellular ATP levels, and improved ROS production.

DFT Study on the CO Reduction to C Chemicals Catalyzed by Fe and Co Clusters Supported on N-Doped Carbon.

The catalytic conversion of CO to C products through the CO reduction reaction (CORR) offers the possibility of preparing carbon-based fuels and valuable chemicals in a sustainable way. Herein, various Fe and Co clusters are designed to screen out the good catalysts with reasonable stability, as well as high activity and selectivity for either CH or CHCHOH generation through density functional theory (DFT) calculations. The binding energy and cohesive energy calculations show that both Fe and Co clusters can adsorb stably on the N-doped carbon (NC) with one metal atom anchored at the center of the defected hole via a classical MN structure.

Cu activated persulfate for sulfamethazine degradation.

Sulfonamide antibiotics (SAs) are widely used in veterinary medicine but are poorly metabolized in biological systems; thus, they can cause a selective pressure to promote the proliferation of antibiotic resistant pathogens and threaten human health. Persulfate (PS)-based advanced oxidation processes (AOPs) have been applied for SA degradation, but using transition metal ions as PS activators is relatively limited. In this study, sulfamethazine (SMZ) was used as a model SA to evaluate the performance of a Cu -activated PS system.