Publications by authors named "Chuanchuan Cai"
Article Synopsis
- Insulin-like growth factor-1 (IGF-1) contributes to acne vulgaris by causing dysfunction in sebaceous glands, and the study focuses on the effects of Paeoniflorin (Pae), a compound derived from paeony, on this process.* -
- The research demonstrated that Pae can inhibit cell growth, promote cell death, and reduce fat and inflammatory substance production in sebocytes exposed to IGF-1.* -
- Pae's anti-acne properties are linked to its ability to affect key signaling pathways (PI3K/Akt/FoxO1 and JAK2/STAT3) that regulate cell proliferation and inflammation.*
The desulfurization efficiency, combustion properties, combustion kinetics, and structural changes of Kentucky coal under microwave irradiation (MI) combined with hydrochloric acid solution pickling were investigated and compared using a thermogravimetric analyzer coupled to a Fourier transform infrared spectrometer. The results show that the desulfurization rate increases with the concentration of hydrochloric acid solution. The introduction of MI can effectively improve the desulfurization efficiency.
View Article and Find Full Text PDFCoking coal is geologically scarce resource and most of them cannot be directly used in steel making due to their higher sulfur content. One desulfurization method that has great potential for massive application is microwave desulfurization, which removes the relatively stubborn organic sulfur under mild conditions. The dielectric properties of coals determine the efficiency of the microwave energy absorption.
View Article and Find Full Text PDFArticle Synopsis
- Becker's naevus is a skin condition linked to androgens, and this study aimed to explore the role of hormone receptors in its development.
- Researchers found that levels of androgen, estrogen, and progesterone receptors were significantly higher in the skin lesions of Becker's naevus compared to surrounding and control skin, suggesting hormone involvement.
- The study indicates that the overexpression of these hormone receptors, particularly in pilosebaceous glands and hair follicles, may play a role in the disorder's pathogenesis.
Sebocyte differentiation is a continuous process, but its potential molecular mechanism remains unclear. We aimed to establish a novel sebocyte differentiation model using human primary sebocytes and to identify the expression profiles of differentiation-associated proteins. Primary human sebocytes were cultured on Sebomed medium supplemented with 2% serum for 7 days.
View Article and Find Full Text PDFBackground: Although Becker's nevus (BN) is a relatively common disease, the systematic studies of clinicopathological and immunohistochemical results are poorly reported.
Objective: To investigate the clinicopathological features and immunohistochemical alterations of keratinocyte proliferation, melanocyte density, smooth muscle hyperplasia and nerve fiber distribution in BN.
Methods: Clinical and pathological data were collected in 60 newly-diagnosed BN cases.
Objective: To observe the changes in peripheral blood lymphocyte subsets in patients with latent syphilis after treatment, who had persistent positive results of test for rapid plasma reagin (RPR) and remained infectious.
Methods: T-lymphocyte subsets and natural killer (NK) cells in peripheral blood were measured with flow cytometry (FCM) in these 43 patients and 30 normal subjects served as controls.
Results: Peripheral blood CD3, CD4 and NK cells exhibited no significant difference between the latent patients and the controls (P>0.