Background: This paper aims to analyze the time trend of OCs incidence in 43 countries (1988-2012) and predict the incidence trend of OCs (2012-2030).
Methods: In the database for Cancer Incidence in Five Continents, the annual data on OCs incidence grouped by age and gender were obtained from 108 cancer registries in 43 countries. The age-standardized incidence rates were calculated, and the Bayesian age-period-cohort model was used to predict the incidence in 2030.
Parathyroid adenoma (PA), one of the most common causes of hyperparathyroidism, generally involves a single parathyroid gland and is manifested as hyperparathyroidism. Bronchogenic cysts are rare congenital cystic lesions caused by a development malformation in bronchi during the embryonic period, which mostly occur in the lung and mediastinum, with an extremely low morbidity rate in the neck. A 27-year-old young female was found to suffer from hyperparathyroidism on routine physical examination, and further examination suggested a cystic lesion in the right inferior parathyroid area combined with a tracheal diverticulum.
View Article and Find Full Text PDFThe hygroscopicity of aerosols is dependent upon their chemical composition. When their chemical compositions are altered, the water content in aerosols often changes, which may further modify phase behaviour. However, the study of phase behaviour dependence on chemical reactions is still limited.
View Article and Find Full Text PDFThe objective of the present study was to investigate the long non-coding RNA (lncRNA) and mRNA expression profiles that are associated with the invasion and metastasis of papillary thyroid carcinoma (PTC). Transwell invasion assays were used to screen three highly invasive sub-strains of the human PTC IHH4 cell line: IHH4-M1, IHH4-M2 and IHH4-M3. In addition, tumor-bearing nude mice were used to identify the invasive and metastatic capacity of the three sub-strains.
View Article and Find Full Text PDFObjectives: The number of metastatic lymph nodes (LNs) and the ratio between the number of metastatic LNs and the total number of retrieved LNs (the LN ratio [LNR]) have been proposed as risk factors for recurrence of papillary thyroid carcinoma (PTC). However, the significance of the number of LNs and the LNR in patients with clinically node negative PTC has not been clearly determined. The purpose of this study is to evaluate their significance.
View Article and Find Full Text PDFObjective: The aim of this study was to investigate the incidence and risk factors for lateral lymph node metastasis (LLNM) in patients with papillary thyroid carcinoma (PTC).
Subjects And Methods: 356 patients diagnosed with PTC who underwent total thyroidectomy and central lymph node dissection and lateral lymph node dissection between January 2005 and December 2011 were enrolled. The relation between LLNM and clinicopathological features such as gender, age, tumor size, tumor spread, psammoma bodies, tumor multifocality, extrathyroidal extension (ETE), unilateral or bilateral disease, tumor primary location and central lymph node metastases (CLNM) was analyzed.
Asia Pac J Clin Oncol
October 2017
Aim: To investigate the clinical significance of the DLN metastasis in papillary thyroid cancer (PTC).
Methods: A total of 231 PTC patients who underwent first surgical treatment in the Department of Hand and Neck Surgery of Zhejiang Cancer Hospital from January 2013 to June 2014 were enrolled. The relationship between Delphian lymph node (DLN) metastasis and patient age, gender, tumor size, tumor number, unilateral or bilateral, capsular invasion, pretracheal and paratracheal node metastasis, and lateral node metastasis was analyzed.
The aim of the present study was to identify potential therapeutic targets for papillary thyroid carcinoma (PTC) and to investigate the possible mechanism underlying this disease. The gene expression profile, GSE53157, was downloaded from the Gene Expression Omnibus database. Only 10 chips, including 3 specimens of normal thyroid tissues and 7 specimens of well-differentiated thyroid carcinomas, were analyzed in the present study.
View Article and Find Full Text PDFPurpose: To analyze the incidence and mortality of oral cavity cancer in the cancer registration areas of China in 2010.
Materials And Methods: Until June 1, 2013, 219 population-based cancer registries submitted the data of 2010 to the National Central Cancer Registry of China covering about 207,229,403 population, and 120 cancer registries were selected after the quality evaluation for this analysis. Oral cavity cancer cases were selected from the database according to the International Classification of Diseases-10 coded as "C00-C10, C11-C12.
Zhonghua Zhong Liu Za Zhi
November 2013
Objective: To investigate the aberrant promoter methylation of hMLH1 gene promoter and its clinical significance in papillary thyroid cancer (PTC).
Methods: methylation of hMLH1 gene promoter in the cancer tissue and matched tumor-adjacent normal tissue of 152 PTC patients were detected by real-time methylation specific PCR (qMSP). The relationship between the methylation of hMLH1 gene promoter and clinicopathological features was analyzed.
Although the hygroscopicity of a NaNO(3)/water microdroplet and a polyalcohol/water microdroplet, two of the most important aerosols in atmosphere, has been widely studied, little is known about the relationship between the hygroscopic behavior of mixed NaNO(3)/polyalcohol/water droplets and their structures on the molecular level. In this study, the hygroscopicity of mixed glycerol/NaNO(3)/water droplets deposited on a hydrophobic substrate was studied by micro-Raman spectroscopy with organic-to-inorganic molar ratios (OIRs) of 0.5, 1, and 2.
View Article and Find Full Text PDFObjective: To investigate the methylation of 5'-CpG island and expression of RUNX3 in salivary gland adenoid cystic carcinoma cell lines.
Methods: RT-PCR (reverse transcription-polymerase chain reaction), laser scanning confocal microscope (LSCM) and Western blot were used to detect the expression of RUNX3 gene and protein in salivary gland adenoid cystic carcinoma cell lines, ACC-2, ACC-3, and ACC-M, before/after a treatment of 5-Aza-dc respectively.
Results: A weak expression of RUNX3 was found in ACC-2 and ACC-3.