Graphene oxide linked sulfonate-based polyanionic nanogels as biocompatible, robust and versatile modifiers of ultrafiltration membranes.

Aiming to enhance the current biological performances of ultrafiltration membranes, in this study, a new kind of graphene oxide linked sulfonate-based polyanionic nanogel (GO-SPN) was fabricated by free radical cross-linked copolymerization. Then, GO-SPN embedded polyethersulfone (PES/GO-SPN) ultrafiltration (UF) membranes were achieved through one-pot PES dissolution and interpenetration, followed by a liquid-liquid phase inversion method. The GO-SPN modified UF membranes exhibited increased porous cross-section structures with a pH-dependent water flux.

Graphene oxide based heparin-mimicking and hemocompatible polymeric hydrogels for versatile biomedical applications.

Studies on the design of heparin and heparin-mimicking polymer based hydrogels are of tremendous interest and are fuelled by diverse emerging biomedical applications, such as antithrombogenic materials, growth factor carriers, and scaffolds for tissue engineering and regeneration medicine. In this study, inspired by the recent developments of heparin-based hydrogels, graphene oxide (GO) based heparin-mimicking hydrogels with hemocompatibility and versatile properties were prepared via free radical copolymerization, and poly(ethylene glycol) methyl ether methacrylate (PEGMA) and 2-hydroxyethyl methacrylate (HEMA) hydrogels were used as the control samples. The GO based heparin-mimicking polymeric hydrogels exhibited interconnected structures with thin pore walls and high porosity.