Publications by authors named "Chuan-Quan Lin"

Objectives: Malnutrition, defined according to Nutritional risk screening (NRS 2002), is commonly observed in patients of Myasthenia gravis (MG), a neuromuscular disorder manifested by varied degrees of skeletal muscle weakness. Because biochemical composition of saliva changes in correspondence to alterations in nutritional status, we tested our hypothesis that a certain saliva component(s) might serve as a biomarker(s) for nutrition status of MG, particularly for those MG patients with high risk of malnutrition.

Materials And Methods: 60 MG patients and 60 subjects belonging to the healthy control group (HCG) were enrolled in this case-control study.

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Background: Saliva composition has diurnal variations. Citric acid stimulation plays a major role in the change of salivary flow rate and salivary composition. However, diurnal variations and sex differences in salivary alpha-amylase (sAA), pH, salivary flow rate (SFR), and salivary cortisol before and after citric acid stimulation remain unclear.

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Background And Aim: Salivary characteristics are altered in gastrointestinal diseases and related to oral taste disorder. However, specific salivary biochemical characteristics and their relationships with oral taste disturbances in chronic non-atrophy gastritis (CNAG) remain uncertain.

Methods: Seventy patients with CNAG and 70 subjects in healthy control group (HCG) were enrolled in our study.

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Article Synopsis
  • The study investigates the effects of polysaccharide extracts from Astragalus membranaceus and Atractylodes macrocephala on the migration of IEC-6 cells, which are a model for gut health.
  • The results indicate that these extracts significantly enhanced cell migration and increased levels of cellular polyamines and calcium, suggesting a potential therapeutic role for these herbs in gastrointestinal diseases.
  • Moreover, the extracts were found to counteract the inhibitory effects of specific compounds on cell migration, indicating their ability to restore normal migratory functions in polyamine-deficient conditions.
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Background: Gender differences in the function and anatomical features of salivary glands are well known. However, specific gender differences in the biochemical composition and salivary flow rate (SFR) remain uncertain. Collection methods affect the assessment of the salivary composition and SFR, which are also highly affected by acid stimulation.

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Purpose: This study compared the effect of 3 saliva collection methods on salivary secretion, in order to select optimum collection method for follow-up studies.

Methods: Fifty-five young healthy volunteers' saliva samples were collected by EP tube collecting emulated with natural flow (ETC), rotating mouth swab slightly (RMS) and chewing mouth swab (CMS) before and after stimulating with acid. The salivary flow rate, salivary alpha-amylase (sAA) activity of each saliva sample and its ratio before and after stimulating with acid were detected to provide the basis for the preferred method of collecting saliva.

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Objective: To study the effect of reserpine (RSP) for changing salivary protein secretion in Pi-deficient rats and to explore its possible mechanism.

Methods: Twenty rats allocated in the RSP group were given subcutaneous injection of RSP [0.4 mg/(kg x d)] for 9 successive days, while the other 20 rats in the control group were injected with same volume of saline instead.

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