Publications by authors named "Chuan He Wang"

Article Synopsis
  • This study evaluates the predictive value of soluble growth stimulation expressed gene 2 protein (sST2) for long-term clinical outcomes in patients with acute heart failure (AHF), particularly focusing on those with a history of myocardial infarction (MI).
  • Researchers followed 149 hospitalized AHF patients over three years and found that higher sST2 levels were significantly associated with major adverse cardiovascular events (MACEs), including heart failure readmissions and mortality.
  • The findings highlight sST2 as a strong predictor for patients with prior MI, suggesting that monitoring sST2 levels could improve patient management in this high-risk group.
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Background: As the global aging process continues to accelerate, heart failure (HF) has become an important cause of increased morbidity and mortality in elderly patients. Chronic atrial fibrillation (AF) is a major risk factor for HF. Patients with HF combined with AF are more difficult to treat and have a worse prognosis.

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Although empagliflozin has been recommended for individuals with heart failure, its effects on heart failure with preserved ejection fraction (HFpEF) remain uncertain from a physiopathological standpoint. The metabolites produced by gut microbiota have been shown to have a crucial role in the development of heart failure. Sodium-glucose cotransporter-2 inhibitors (SGLT2) have been shown to change the make-up of the gut microbiota in rodent studies.

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To develop and validate internally a multivariate risk model for predicting the in-hospital mortality of patients with heart failure with preserved ejection fraction (HFpEF) and heart failure with mid-range ejection fraction (HFmrEF). The clinical data of 8172 inpatients with HFpEF and HFmrEF was used to establish a retrospective database. These patients, among whom 307 in-hospital deaths (3.

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