Publications by authors named "Chu-Chu Wang"

The rice leaf folder, (Lepidoptera: Pyralidae), is a notorious pest of rice in Asia. The larvae and adults of utilize specialized chemosensory systems to adapt to different environmental odors and physiological behaviors. However, the differences in chemosensory genes between the olfactory organs of these two different developmental stages remain unclear.

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Doxorubicin (DOX), is a high efficiency anthracycline antitumor drug. However, the clinical application of DOX is limited mainly by dose-related adverse drug reactions. Currently, the therapeutic effects of Atorvastatin (ATO) on DOX-induced hepatotoxicity were studied in vivo.

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Background And Objectives: Intensive care unit-acquired weakness (ICU-AW) commonly occurs among intensive care unit (ICU) patients and seriously affects the survival rate and long-term quality of life for patients. In this systematic review, we synthesized the findings of previous studies in order to analyze predictors of ICU-AW and evaluate the discrimination and validity of ICU-AW risk prediction models for ICU patients.

Methods: We searched seven databases published in English and Chinese language to identify studies regarding ICU-AW risk prediction models.

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Article Synopsis
  • The TSLP/TSLPR axis plays a significant role in inflammatory diseases, including coronary artery disease (CAD), with a study analyzing genetic variants in this axis among a large population of CAD patients and controls.
  • Three specific genetic variants were found to have a strong association with CAD, with rs3806933 and rs6897932 notably affecting the expression of related genes and potentially increasing plasma TSLP levels.
  • The research indicates that these genetic variants, both individually and in combination (particularly with IL-33 signaling), contribute to a heightened risk of developing CAD, suggesting a complex genetic influence on the disease.
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Objective: The outcome of atrial fibrillation patients with genetic mutations post ablation was not well evaluated.

Methods And Results: Three atrial fibrillation patients with evidence of mutations in KCNA5 and NPPA post successful circumferential pulmonary vein ablation were included. Mutation in KCNA5 was found in one male patient with paroxysmal atrial fibrillation.

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Coronary artery disease (CAD) causes more than 700,000 deaths each year in China. Previous genome-wide association studies (GWAS) in populations of European ancestry identified several genetic loci for CAD, but no such study has yet been reported in the Chinese population. Here we report a three-stage GWAS in the Chinese Han population.

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