Publications by authors named "Chu King Sun"
Objectives: The study aimed to evaluate the frequency of incidental suspicious lesions detected by flourine-18 fluorodeoxyglucose PET/computed tomography ( 18 F-FDG PET/CT) scans done for staging or restaging in adult cancer patients. We further determined the detection rate of synchronous and metachronous malignancies in these suspicious lesions after further investigations.
Materials And Methods: This retrospective analysis evaluated the consecutive patients with 18 F-FDG PET/CT scans done in Queen Elizabeth Hospital (QEH), Hong Kong between July 2021 and June 2022.
Article Synopsis
- The study conducts a systematic review and meta-analysis to evaluate the effectiveness of 18 F-FDG PET imaging in identifying brain metastases arising from various cancers, revealing potential differences in imaging outcomes based on the type of cancer.
- Among the 2227 patients analyzed from 11 studies, the findings indicated a low sensitivity (44%) but high specificity (99%) of FDG PET for detecting brain metastases, with significant variability in results across studies.
- The analysis suggests that awareness of asymmetrical hypometabolism could enhance the sensitivity of FDG PET, indicating a need for further research to refine diagnostic techniques.
Article Synopsis
- The study focuses on identifying factors that impact progression-free survival in patients with metastatic lung adenocarcinoma treated with tyrosine kinase inhibitors (TKIs).
- Statistical analysis of 41 patients revealed that primary tumor SUV, serum CEA levels, gender, and smoking history are significant prognostic indicators.
- Specifically, lower SUV and serum CEA levels, being female, and having a history of never smoking suggest a better response to TKI treatment.