Metabolic syndrome in obese adolescents is associated with risk for nephrolithiasis.

Objectives: To examine the relationship between urinary pH and metabolic syndrome risk factors along with insulin resistance in obese adolescents, and to evaluate the relationship between other urinary stone-forming and -inhibiting markers and metabolic syndrome.

Study Design: A total of 46 obese adolescents were enrolled. Twenty-four hour and randomly obtained urine samples were analyzed for urinary pH, promoters of stone formation (ie, uric acid, oxalate, and relative saturation ratio of calcium oxalate [RSR-CaOx]), and inhibitors of stone formation (ie, citrate and osteopontin).

The abnormal measures of iron homeostasis in pediatric obesity are associated with the inflammation of obesity.

Objectives. To determine if the low iron state described in obese children is associated with the chronic inflammatory state seen in obesity. Study Design.