Calmodulin, Calcium/Calmodulin-Dependent Kinases-1 and 2 Regulate Expression of the Heat Shock Proteins for Heat Shock Tolerance and Pheromone Signaling Genes for Sexual Development in .

Unlabelled: Calmodulin (CaM) is a primary Ca sensor that binds and activates numerous target proteins and regulates several cellular processes in eukaryotes. CaM is essential in ; therefore, we generated a CaM mutant using repeat-induced point (RIP) mutation and investigated the mutant phenotypes. We also studied knockout mutants of four Ca/CaM kinases (, , , and ) for their role during stress conditions and sexual development.

Multiple calcium signaling genes play a role in the circadian period of Neurospora crassa.

The Ca2+ signaling genes cpe-1, plc-1, ncs-1, splA2, camk-1, camk-2, camk-3, camk-4, cmd, and cnb-1 are necessary for a normal circadian period length in Neurospora crassa. In addition, the Q10 values ranged between 0.8 and 1.