George N. Papanicolaou (1883-1962): The Pioneer of Cytology and Early Cancer Detection.

George N. Papanicolaou (1883-1962) is recognized as a pioneer in cytology and early cancer detection, whose groundbreaking work revolutionized women's healthcare. His development of the Pap smear, a simple yet powerful screening tool, dramatically improved the early diagnosis of cervical cancer, leading to a significant reduction in mortality rates and saving millions of lives worldwide.

John Snow: The Pioneer of Modern Epidemiology and Anesthesia.

John Snow (15 March 1813-16 June 1858) stands as a seminal figure in the fields of epidemiology and anesthesia. His groundbreaking work in tracing the source of cholera outbreaks and advancing the practice of anesthesia has left an indelible mark on modern medicine. Born in York, England, Snow's early passion for science and dedication to medical practice led him to become a pioneering force in his field.

Survival Analysis of Elderly Patients With Laryngeal Cancer After Total Laryngectomy: A Retrospective Cohort Study.

Objective This study investigates the overall survival (OS) of elderly patients who underwent total laryngectomy for laryngeal cancer (LC) and examines the impact of tumor-node-metastasis (TNM) staging on survival rates. Methods A retrospective cohort study utilized data from the Otorhinolaryngology Clinic at the University Hospital of Patras, including 75 elderly patients (>65 years) who underwent total laryngectomy for LC between 2000 and 2015. Survival analysis was performed using the Kaplan-Meier estimator, with comparisons made using the Log-rank test.

Epidemiological Characteristics and Survival Analysis of Patients With Nasopharyngeal Cancer in Western Greece.

Purpose The purpose of this study is to assess the overall survival (OS) of patients with nasopharyngeal cancer and the factors affecting the survival rates. Methods A retrospective cohort study was performed, including 77 patients with nasopharyngeal cancer diagnosed and treated in the Otorhinolaryngology Clinic of the University Hospital of Patras during 1990-2017. The prognostic impact of age, gender, occupation, smoking/alcohol, and TNM staging were evaluated using Kaplan-Meier analysis.