Publications by authors named "Christos Profilis"
Article Synopsis
- Routine pancreatic lipase assays lack standardization, leading to poor comparability between methods primarily due to the absence of reference materials (RMs).
- This study aimed to establish the catalytic concentration values for two human pancreatic lipase RMs, one derived from pancreatic juice and the other produced through recombinant techniques, using a standardized testing approach across multiple labs.
- Results showed acceptable performance with mean values for the RMs (BCR 693 and 694) and suggested that these can be used to ensure accurate implementation of testing procedures and enhance consistency of lab results in line with regulatory standards.
There is a lack of certified reference material (CRM) for lipase catalytic activity. Consequently between-method comparability is very poor. The aim of this study was to produce two lipase CRMs, one from human pancreatic juice (BCR 693), and another using recombinant technologies (BCR 694).
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