Publications by authors named "Christos Paschalides"

Article Synopsis
  • The study aimed to assess the effectiveness of CoSeal® surgical sealant in reducing prolonged alveolar air leaks after lung surgeries.
  • It involved 121 patients who had an air leak during surgery, with half receiving standard care and the other half receiving standard care plus CoSeal®.
  • The results showed that while some patients initially stopped leaking, overall, those treated with CoSeal® experienced longer air leak durations, leading researchers to conclude that the sealant should not be routinely used.
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Objective: To assess the feasibility and acceptability of obtaining data on prescribing error rates in routine practice, and presenting feedback on such errors to medical staff.

Setting: One clinical directorate of a London teaching trust.

Methods: Ward pharmacists recorded all prescribing errors identified in newly written medication orders on one day each fortnight between February and May 2005.

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We sought to establish the extent to which tumour uptake of [18F]-fluoro2-deoxy-glucose is associated with survival in patients with primary lung cancer. From our analysis of data concerning 498 lung cancer patients, including surgical and non-surgical cases, we conclude that there is a clear association between higher tumour uptake of glucose and worse survival.

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Faced with the problem of giving individualised advice about adjuvant chemotherapy to patients who have had an apparently curative lung cancer resection, we propose a model to help clarify the choices being made. This would inform the clinician, help the patient and be an explicit basis on which to initiate the discussion.

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