Publications by authors named "Christos Pagonis"
Background: The registry-based randomized VALIDATE-SWEDEHEART trial (NCT02311231) compared bivalirudin vs. heparin in patients undergoing percutaneous coronary intervention (PCI) for myocardial infarction (MI). It showed no difference in the composite primary endpoint of death, MI, or major bleeding at 180 days.
View Article and Find Full Text PDFDiagnostic performance of a novel deep learning attenuation correction software for MPI using a cardio dedicated CZT camera. Experience in the clinical practice.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
January 2024
Article Synopsis
- A study evaluated a new software (DLACS) designed to improve the accuracy of myocardial perfusion imaging (MPI) for diagnosing coronary artery disease (CAD) in high-risk patients using a specialized camera.
- The research involved 300 patients, analyzing the accuracy of MPI with and without DLACS in comparison to invasive coronary angiography for CAD diagnosis.
- Results showed that DLACS increased diagnostic accuracy from 87% to 90%, emphasizing better specificity and positive predictive value, which reduces false positives and improves overall performance.
Diagnostic performance of different cardiac stress protocols for myocardial perfusion imaging for the diagnosis of coronary artery disease using a cadmium-zinc-telluride camera with invasive coronary angiography correlation.
Rev Esp Med Nucl Imagen Mol (Engl Ed)
September 2022
Article Synopsis
- The study evaluates the effectiveness of three cardiac stress testing methods for diagnosing coronary artery disease (CAD) using a specific imaging technology and compares results with invasive coronary angiography.
- It analyzed 263 patients over four years, focusing on those who underwent bicycle stress tests, pharmacological stress tests, or a combination of both.
- Findings showed no significant differences in the diagnostic accuracy of the stress protocols, with an overall MPI accuracy of 86%, indicating the CZT D-SPECT camera performed well in diagnosing CAD.
Objectives: The aim of this study was to conduct a nationwide all comer description of incidence, contemporary management and outcome in Swedish spontaneous coronary artery dissection (SCAD) patients. The incidence of SCAD as well as the management and outcome of these patients is not well described.
Design: A nationwide observational study.
Purpose: Evaluate the prediction of quantitative coronary angiography (QCA) values from MPI, by means of deep learning.
Methods: 546 patients (67% men) undergoing stress 99mTc-tetrofosmin MPI in a CZT camera in the upright and supine position were included (1092 MPIs). Patients were divided into two groups: ICA group included 271 patients who performed an ICA within 6 months of MPI and a control group with 275 patients with low pre-test probability for CAD and a normal MPI.
Background: Radial artery is the preferred access site in contemporary percutaneous coronary intervention (PCI). However, limited data exist regarding utilization pattern, safety, and long-term efficacy of transradial artery access (TRA) PCI in heavily calcified lesions using high-speed rotational atherectomy (HSRA).
Methods: All patients who underwent HSRA-PCI in Sweden between 2005 and 2016 were included.
Skin injuries may occur when radiation doses to the skin exceed 2 Gy. This study aimed to measure changes in skin microcirculation in patients undergoing chronic total occlusion percutaneous coronary interventions (CTO-PCI). In 14 patients, peak skin dose (PSD) was estimated with radiographic films and skin microcirculation was assessed with laser speckle contrast imaging (LSCI), before, 1 day after the intervention, and 4-6 weeks later.
View Article and Find Full Text PDFBackground: This study examines whether preceding assessment of periodontal status in patients with established coronary artery disease (CAD) can predict future CAD endpoints (myocardial infarction, new revascularization procedure, or CAD-related death) during 8-year follow-up and whether the changes in periodontal status over time differ in patients with CAD compared with healthy controls.
Methods: In 2003, periodontal status was examined in 161 patients with CAD who underwent percutaneous coronary intervention or coronary artery bypass graft due to significant stenosis in the coronary arteries and 162 controls without CAD. Eight years later, 126 patients with CAD (102 males and 24 females, mean age: 68 ± 8.