Development of a simple paste for 3D printing of drug formulations containing a mesoporous material loaded with a poorly water-soluble drug.

Poorly soluble drugs represent a substantial portion of emerging drug candidates, posing significant challenges for pharmaceutical formulators. One promising method to enhance the drug's dissolution rate and, consequently, bioavailability involves transforming them into an amorphous state within mesoporous materials. These materials can then be seamlessly integrated into personalized drug formulations using Additive Manufacturing (AM) techniques, most commonly via Fused Deposition Modeling.

Chitosan nanocomposite coatings with enhanced corrosion inhibition effects for copper.

A biopolymer coating on copper was prepared based on chitosan nanocomposite and its corrosion inhibition efficiency was investigated. Inclusion of silica nanoparticles substantially reduces swelling ratio of chitosan coating while enhancing its thermal stability. The corrosion resistance of chitosan-based coatings is improved by introducing 2-mercaptobenzothiazole and silica in the matrix.