Seismic assessment of bridges through structural health monitoring: a state-of-the-art review.

The present work offers a comprehensive overview of methods related to condition assessment of bridges through Structural Health Monitoring (SHM) procedures, with a particular interest on aspects of seismic assessment. Established techniques pertaining to different levels of the SHM hierarchy, reflecting increasing detail and complexity, are first outlined. A significant portion of this review work is then devoted to the overview of computational intelligence schemes across various aspects of bridge condition assessment, including sensor placement and health tracking.

MFGE-8 identified in fetal mesenchymal-stromal-cell-derived exosomes ameliorates acute hepatic failure pathology.

Liver transplantation is the gold-standard therapy for acute hepatic failure (AHF) with limitations related to organ shortage and life-long immunosuppressive therapy. Cell therapy emerges as a promising alternative to transplantation. We have previously shown that IL-10 and Annexin-A1 released by amniotic fluid human mesenchymal stromal cells (AF-MSCs) and their hepatocyte progenitor-like (HPL) or hepatocyte-like (HPL) cells induce liver repair and downregulate systemic inflammation in a CCl-AHF mouse model.

Extracellular vesicles derived from mesenchymal stem/stromal cells: The regenerative impact in liver diseases.

Liver dysfunctions are classified into acute and chronic diseases, which comprise a heterogeneous group of pathological features and a high mortality rate. Liver transplantation remains the gold-standard therapy for most liver diseases, with concomitant limitations related to donor organ shortage and lifelong immunosuppressive therapy. A concept in liver therapy intends to overcome these limitations based on the secreted extracellular vesicles (EVs; microvesicles and exosomes) by mesenchymal stem/stromal cells (MSCs).

A Low-Cost Instrumentation System for Seismic Hazard Assessment in Urban Areas.

The development and application of a low-cost instrumentation system for seismic hazard assessment in urban areas are described in the present study. The system comprises a number of autonomous triaxial accelerographs, designed and manufactured in house and together with dedicated software for device configuration, data collection and further postprocessing. The main objective is to produce a detailed view of strong motion variability in urban areas, for at least light intensity strong motion events.