The accurate "base pairing" in RNA molecules, which leads to the prediction of RNA secondary structures, is crucial in order to explain unknown biological operations. Recently, COVID-19, a widespread disease, has caused many deaths, affecting humanity in an unprecedented way. SARS-CoV-2, a single-stranded RNA virus, has shown the significance of analyzing these molecules and their structures.
View Article and Find Full Text PDFObtaining valuable clues for noncoding RNA (ribonucleic acid) subsequences remains a significant challenge, acknowledging that most of the human genome transcribes into noncoding RNA parts related to unknown biological operations. Capturing these clues relies on accurate "base pairing" prediction, also known as "RNA secondary structure prediction". As COVID-19 is considered a severe global threat, the single-stranded SARS-CoV-2 virus reveals the importance of establishing an efficient RNA analysis toolkit.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
January 2019
This paper describes a novel web-based platform promoting real-time advanced teleconsultation services on medical imaging. Principles of heterogeneous workflow management systems and state-of-the-art technologies such as the microservices architectural pattern, peer-to-peer networking, and the single-page application concept are combined to build a scalable and extensible platform to aid collaboration among geographically distributed healthcare professionals. The real-time communication capabilities are based on the webRTC protocol to enable direct communication among clients.
View Article and Find Full Text PDFThe paper deals with the design of a Web-based platform for real-time medical teleconsultation on medical images. The proposed platform combines the principles of heterogeneous Workflow Management Systems (WfMSs), the peer-to-peer networking architecture and the SPA (Single-Page Application) concept, to facilitate medical collaboration among healthcare professionals geographically distributed. The presented work leverages state-of-the-art features of the web to support peer-to-peer communication using the WebRTC (Web Real Time Communication) protocol and client-side data processing for creating an integrated collaboration environment.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
August 2015
The gradual shift in modern medical practice, from working alone clinical doctors to MDTs (Multi-Disciplinary Teams), raises the need of online real-time collaboration among geographically distributed medical personnel. The paper presents a Web-based platform, featuring an efficient medical data management and exchange, for hosting real-time collaborative services. The presented work leverages state-of-the-art features of the web (technologies and APIs) to support client-side medical data processing.
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