Publications by authors named "Christopher Van Hise"
Background: Low concentrations of cardiac troponin (cTn) have been recommended for rapid rule-out of acute myocardial infarction (AMI). We examined the Beckman Coulter Access high-sensitivity cardiac troponin I (hs-cTnI) assay to identify a single test threshold that can safely rule out AMI.
Methods: This analysis used stored samples collected in 2 prospective observational studies.
Article Synopsis
- The study aimed to evaluate the effectiveness of five chest pain assessment pathways using a new high-sensitivity troponin I test in patients attending an emergency department.
- Involving 1,811 patients, it assessed how well these pathways could classify patients as low risk for acute myocardial infarction and acute coronary syndrome.
- Results showed that the Vancouver Chest Pain Rule and No Objective Testing Rule had the highest sensitivity for detecting serious conditions, while the other three pathways (m-ADAPT, EDACS, HEART) identified more patients as low risk but had slightly lower sensitivity.
Objective: To externally validate a clinical decision rule incorporating heart fatty acid binding protein (h-FABP), high-sensitivity troponin (hs-cTn) and electrocardiogram (ECG) for the detection of acute myocardial infarction (AMI) on presentation to the Emergency Department. We also investigated whether this clinical decision rule improved identification of AMI over algorithms incorporating hs-cTn and ECG only.
Design And Methods: This study included data from 789 patients from the Brisbane ADAPT cohort and 441 patients from the Christchurch TIMI RCT cohort.
Objectives: The objective was to examine cannulation practice and effectiveness of a multimodal intervention to reduce peripheral intravenous cannula (PIVC) insertion in emergency department (ED) patients.
Methods: A prospective before and after study and cost analysis was conducted at a single tertiary ED in Australia. Data were collected 24 hours a day for 2 weeks pre- and post implementation of a multimodal intervention.