Publications by authors named "Christopher Shea"

Background: Academic health centers (AHCs) have traditionally focused on 3 core missions: patient care, research, and education. The current changing health care environment requires AHCs to broaden their focus to improve the health of their communities. This study reports the opportunities and challenges for the 5 North Carolina AHCs addressing social determinants of health (SDOH).

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  • Dr. Martin C. Mihm, Jr. contributed significantly to the World Health Organisation Classification of Skin Tumours with his work on dysplastic nevi, emphasizing a dual classification system based on grade.
  • His proposed method includes a quantitative assessment of melanocytic nuclear enlargement, enhancing the evaluation of these skin lesions.
  • The paper also aims to refine existing grading systems by integrating WHO-C definitions and improving the Duke classification's quantitative and architectural criteria for better assessment of dysplastic nevi.
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The COVID-19 pandemic brought about a drastic increase in the utilization of telehealth services in place of or as a complement to in-person health services. Telehealth is a tool to help reduce disparities in the receipt of maternal health care. However, a stable internet connection is required for patients to connect to providers via telehealth; lack of internet connectivity is a barrier to maternal telehealth access.

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  • Implementation science research highlights the importance of clinical champions in aligning healthcare professionals' behaviors with vaccination guidelines, but more understanding is needed on how to identify and support these champions.
  • A study in 2022 interviewed identified vaccine champions and their colleagues, revealing that champions often come from primary care backgrounds and believe strongly in the effectiveness of vaccines for prevention.
  • Findings suggest that supporting these champions with dedicated time and resources can enhance their role in educating others, thereby improving vaccination rates within pediatric primary care settings.
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Quality checklists have demonstrated benefits in healthcare and other high-reliability organizations, but there remains a gap in the understanding of design approaches and levels of stakeholder engagement in the development of these quality checklists. This scoping review aims to synthesize the current knowledge base regarding the use of various design approaches for developing quality checklists in healthcare. Secondary objectives are to explore theoretical frameworks, design principles, stakeholder involvement and engagement, and characteristics of the design methods used for developing quality checklists.

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  • Poly-L-lactic acid (PLLA) is an injectable filler that helps restore facial fat volume and enhances skin quality, particularly in women.
  • A study involving 10 healthy women compared the effects of PLLA against a placebo over three treatments, assessing changes in skin quality and histological characteristics.
  • Results showed significant improvements in skin quality, reduced wrinkles, and favorable tissue changes like increased remodeling and blood vessel formation in the PLLA group without any major side effects.
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Exposure to inorganic arsenic (As) is recognized as a risk factor for non-melanoma skin cancer (NMSC). We followed up with 7000 adults for 6 years who were exposed to As. During follow-up, 2.

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  • Implementation science helps get effective programs into real-life use faster by focusing on how to do it better.
  • A team sorted different strategies for implementing these programs into three main categories: what to do during the process, ways to improve knowledge and skills, and methods to tackle specific challenges.
  • They created a simple five-step plan to help organizations use these strategies effectively, making it easier to put new health programs into practice.
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Background: Differential access to healthcare is associated with disparities in maternal outcomes. Telehealth is one approach for improving access to maternal services. However, little is known regarding how health systems leverage telehealth to close the access gap.

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Objective: The objective was to estimate the rural-urban differences in the receipt of prepregnancy, prenatal, and postpartum services.

Methods: The authors conducted a cross-sectional data analysis using data from the Pregnancy Risk Assessment and Monitoring System from 2016 to 2018 to analyze rural-urban differences in the receipt of medical visits and care content delivery during the prepregnancy year, as well as the prenatal and postpartum periods among birthing people in the US, using survey-weighted multivariable logistic regression models.

Results: Rural-dwelling birthing people were significantly less likely to attend a medical visit in the prepregnancy year or postpartum period, even when controlled for sociodemographic and clinical characteristics.

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  • * It has been linked to the development of certain secondary tumors, primarily from follicular germ cells.
  • * The authors present three cases where individuals had both a melanocytic nevus and nevus sebaceus to illustrate this uncommon occurrence.
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  • Drivers of Spitz neoplasms are linked to mutations in HRAS and genomic fusions, while some BRAF-mutated melanocytic neoplasms can resemble Spitz tumors, leading to the classification known as BRAF mutated and morphologically spitzoid (BAMS).
  • A study involving 17 pathologists assessed 54 cases, including 40 BAMS and 14 true Spitz tumors, without access to genomic data, and found a split in diagnostic preferences with about 38% identifying BAMS and 32% identifying ST among BAMS cases.
  • The study highlighted significant difficulty in distinguishing BAMS from true Spitz tumors, with poor agreement among experts on precise diagnosis (kappa = 0.16), although there was
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Background: Implementation science researchers often cite clinical champions as critical to overcoming organizational resistance and other barriers to the implementation of evidence-based health services, yet relatively little is known about who champions are or how they effect change. To inform future efforts to identify and engage champions to support HPV vaccination, we sought to describe the key characteristics and strategies of vaccine champions working in adolescent primary care.

Methods: In 2022, we conducted a national survey with a web-based panel of 2527 primary care professionals (PCPs) with a role in adolescent HPV vaccination (57% response rate).

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Introduction: Quality improvement collaboratives (QICs) are a common approach to facilitate practice change and improve care delivery. Attention to QIC implementation processes and outcomes can inform best practices for designing and delivering collaborative content. In partnership with a clinically integrated network, we evaluated implementation outcomes for a virtual QIC with independent primary care practices delivered during COVID-19.

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Objective: This study aimed to describe perspectives from stakeholders involved in the Medicaid system in North Carolina regarding substance use disorder (SUD) treatment policy changes during the coronavirus disease 2019 pandemic.

Methods: We conducted semistructured interviews in early 2022 with state agency representatives, Medicaid managed care organizations, and Medicaid providers (n = 22) as well as 3 focus groups of Medicaid beneficiaries with SUD (n = 14). Interviews and focus groups focused on 4 topics: policies, meeting needs during COVID, demand for SUD services, and staffing.

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Despite the policy recommendation and effectiveness of administering the hepatitis B birth-dose vaccine (HepB-BD) to newborns to prevent mother-to-child hepatitis B transmission, timely uptake remains an issue. Countries adopting the HepB-BD to their national immunization schedule report programmatic challenges to administering the vaccine within the recommended 24-hour window after delivery. Further, while the World Health Organization recommends streamlining three birth-dose vaccines (HepB-BD, BCG, and OPV0), scarce Sub-Saharan(SSA)-based literature reports on a streamlined and timely approach to birth-dose vaccines.

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  • Immunization rates in sub-Saharan Africa, particularly for BCG and HepB3 vaccines, are low, and a study in DRC aims to identify factors that affect timely vaccinations at birth to improve coverage.* -
  • The study utilized ordered regression models to analyze survey data from 2398 women-infant pairs, focusing on barriers to receiving vaccinations and exploring determinants influenced by maternal education, wealth, and facility readiness.* -
  • Results revealed that a significant percentage of infants received BCG and HepB3 vaccines, with better outcomes linked to factors like maternal education and facility ownership, highlighting areas for intervention to enhance immunization efforts.*
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Background: Caregivers FIRST is an evidence-based program addressing gaps in caregivers' skills. In 2020, the Veterans Health Administration Caregiver Support Program (CSP) nationally endorsed Caregivers FIRST, offering credit in leadership performance plans to encourage all VA medical centers (VAMCs) to implement locally. This study examines the association of organizational readiness with VAMC adoption of Caregivers FIRST.

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Mycosis fungoides has previously been reported in 'invisible' form, when biopsy of normal-appearing skin in the background of undifferentiated chronic pruritus demonstrated histopathologic findings of the malignancy. Asymptomatic cases have been reported more infrequently on biopsies of individual skin lesions. We present a case of invisible and asymptomatic mycosis fungoides, confirmed with immunohistochemical and T-cell receptor gene rearrangement studies, diagnosed on a re-excision specimen of an atypical melanocytic nevus.

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Endovascular procedures that use a hydrophilic polymer-coated device carry a risk of embolization and ischemic complications when used intravascularly. Because these coatings are increasingly used worldwide, it is important to identify potential adverse effects early. Cutaneous complications of hydrophilic polymer emboli are rare and not commonly described in the literature.

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Background: There is considerable variation in the literature regarding the dermatopathologic diagnostic features of and reporting guidelines for actinic keratosis (AK) and cutaneous squamous cell carcinoma (cSCC).

Objective: To develop consensus recommendations regarding diagnostic criteria, nomenclature, and reporting of AK and cSCC.

Methods: Literature review and cross-sectional multiround Delphi process including an international group of expert dermatopathologists followed by a consensus meeting.

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