Exercise Preferences, Barriers, and Facilitators of Individuals With Cancer Undergoing Chemotherapy Before Stem Cell Transplantation: A Mixed-Methods Study.

Background: Exercise can help mitigate side effects of hematopoietic stem cell transplantation (HSCT), particularly when initiated before HSCT. However, the exercise-related barriers, facilitators, and preferences of this population remain unclear.

Objective: This study aimed to explore the patient experience to inform future implementation of a prehabilitation intervention.

Virtual or In-Person: A Mixed Methods Survey to Determine Exercise Programming Preferences during COVID-19.

A survey was conducted to identify barriers and facilitators to engaging in virtual and in-person cancer-specific exercise during COVID-19. A theory-informed, multi-method, cross-sectional survey was electronically distributed to 192 individuals with cancer investigating preferences towards exercise programming during COVID-19. Respondents had previously participated in an exercise program and comprised two groups: those who had experience with virtual exercise programming ('Virtual') and those who had only taken part in in-person exercise ('In-Person').

Feasibility of Implementing Cancer-Specific Community-Based Exercise Programming: A Multi-Centre Randomized Trial.

Background: There is growing recognition of the importance of reporting preliminary work on the feasibility of a trial. The present study aimed to assess the feasibility of (1) a proposed fitness testing battery, and (2) processes related to the implementation of cancer-specific exercise programming in a community setting.

Methods/design: A randomized controlled implementation feasibility trial was performed in advance of a large-scale implementation study.

A Practical Approach to Using Integrated Knowledge Translation to Inform a Community-Based Exercise Study.

Background: Our aim was to understand cancer survivor needs prior to, and following the Alberta Cancer Exercise (ACE) pilot randomized trial as a means to inform implementation of a province-wide cancer-specific, community-based exercise program.

Methods: Questionnaires and semi-structured stakeholder engagement sessions were conducted with cancer survivors to explore preferences, barriers and facilitators/benefits at two timepoints: (1) pre-ACE: prior to initiation of the ACE pilot trial ( = 13 survivors and = 5 caregivers); and (2) post-ACE: following participation in the ACE pilot trial ( = 20 survivors). Descriptive statistics were used to summarize quantitative data from questionnaires.

Feasibility and efficacy of a 12-week supervised exercise intervention for colorectal cancer survivors.

Exercise training improves health-related physical fitness and patient-reported outcomes in cancer survivors, but few interventions have targeted colorectal cancer (CRC) survivors. This investigation aimed to determine the feasibility and efficacy of a 12-week supervised exercise training program for CRC survivors. Feasibility was assessed by tracking participant recruitment, loss to follow-up, assessment completion rates, participant evaluation, and adherence to the intervention.

Patient satisfaction with participation in a randomized exercise trial: effects of randomization and a usual care posttrial exercise program.

Background: Participation in an exercise trial is a major commitment for cancer survivors, but few exercise trials have evaluated patient satisfaction with trial participation.

Purpose: To examine patient satisfaction with participation in the Healthy Exercise for Lymphoma Patients (HELP) Trial and to explore possible determinants.

Methods: The HELP Trial randomized 122 lymphoma patients to 12 weeks of supervised aerobic exercise training (AET; n = 60) or to usual care (UC; n = 62), with the option of participating in a 4-week posttrial exercise program.

A randomized trial of aerobic exercise and sleep quality in lymphoma patients receiving chemotherapy or no treatments.

Background: Patients with lymphoma experience sleep problems that may be managed with aerobic exercise but no previous study has examined this issue.

Methods: We randomized 122 patients with lymphoma to usual care (n = 62) or 12 weeks of supervised aerobic exercise training (AET; n = 60). Our primary sleep endpoint was global sleep quality assessed by the Pittsburgh Sleep Quality Index (PSQI).

Effects of supervised exercise on motivational outcomes and longer-term behavior.

Introduction: Supervised exercise may have positive effects on motivation and continued exercise in cancer survivors, but few randomized controlled trials have examined this issue. Here, we report the motivational outcomes and longer-term exercise behavior from the Healthy Exercise for Lymphoma Patients trial.

Methods: Lymphoma patients were randomly assigned to 12 wk of supervised aerobic exercise (SUP, n = 60) or usual care (UC, n = 62).

Predictors of follow-up exercise behavior 6 months after a randomized trial of supervised exercise training in lymphoma patients.

Objectives: Supervised exercise is beneficial for lymphoma patients, but it needs to be maintained to optimize long-term benefits. Here, we report the predictors of follow-up exercise behavior 6 months after a randomized controlled trial in lymphoma patients.

Methods: Lymphoma patients were randomly assigned to 12 weeks of supervised aerobic exercise (n = 60) or usual care (n = 62).

Physical activity and gastrointestinal cancer survivorship.

Research examining physical activity in gastrointestinal cancer survivors is in its early stages and has focused primarily on colorectal cancer. Moreover, the majority of the research to date has been observational in nature, with very little interventional research. Though limited, the results of this research have been promising in nature, showing positive associations between physical activity and quality of life as well as disease outcomes, including improved disease-free and overall survival.

Predictors of adherence to supervised exercise in lymphoma patients participating in a randomized controlled trial.

Exercise improves health in lymphoma patients but the determinants of adherence in this population are unknown. The purpose of this study is to examine predictors of exercise adherence in lymphoma patients. In a randomized trial, 60 lymphoma patients were assigned to the exercise group and asked to attend three supervised exercise sessions per week for 12 weeks.

Moderator effects in a randomized controlled trial of exercise training in lymphoma patients.

Background: The Healthy Exercise for Lymphoma Patients trial showed that aerobic exercise training improved important health outcomes in lymphoma patients. Here, we examine potential moderators of the exercise training response.

Methods: Lymphoma patients were stratified by major disease type and current treatment status and randomly assigned to usual care (n = 62) or aerobic exercise training (n = 60) for 12 weeks.

Randomized controlled trial of the effects of aerobic exercise on physical functioning and quality of life in lymphoma patients.

Purpose: Lymphoma patients commonly experience declines in physical functioning and quality of life (QoL) that may be reversed with exercise training.

Patients And Methods: We conducted a randomized controlled trial in Edmonton, Alberta, Canada, between 2005 and 2008 that stratified 122 lymphoma patients by major disease type and current treatment status and randomly assigned them to usual care (UC; n = 62) or 12 weeks of supervised aerobic exercise training (AET; n = 60). Our primary end point was patient-rated physical functioning assessed by the Trial Outcome Index-Anemia.

Correlates of adherence to supervised exercise in patients awaiting surgical removal of malignant lung lesions: results of a pilot study.

Purpose/objectives: To examine the demographic, medical, and social-cognitive correlates of adherence to a presurgical exercise training intervention in patients awaiting surgery for suspected malignant lung lesions.

Design: Pilot study, single-group, prospective design with convenience sampling.

Setting: Exercise training was performed at a university research fitness center in western Canada.

Effects of presurgical exercise training on quality of life in patients undergoing lung resection for suspected malignancy: a pilot study.

The aim of this study was to explore the effects of presurgical exercise training on quality of life (QOL) in patients with malignant lung lesions. Using a single-group prospective design, patients were enrolled in supervised aerobic exercise training for the duration of surgical wait time (mean 59.7 days).

Effect of hydration status on high-intensity rowing performance and immune function.

Purpose: This study determined the effect of dehydration and rehydration (DR) on performance, immune cell response, and tympanic temperature after high-intensity rowing exercise.

Methods: Seven oarswomen completed two simulated 2000-m rowing race trials separated by 72 h in a random, cross-over design. One trial was completed in a euhydrated (E) condition and the other using a DR protocol.

Effects of aerobic exercise training in anemic cancer patients receiving darbepoetin alfa: a randomized controlled trial.

Background: Anemia in patients with solid tumors is a common problem that is associated with impaired exercise capacity, increased fatigue, and lower quality of life (QoL). Erythropoiesis-stimulating agents (ESAs) have been shown to improve these outcomes; however, it is unknown if additional benefits can be achieved with aerobic exercise training.

Methods: We conducted a single-center, prospective, randomized, controlled trial in 55 mild-to-moderately anemic patients with solid tumors.

The effect of dietary control and carbohydrate supplementation on the immune and hormonal responses to rowing exercise.

To determine the effect of carbohydrate supplementation on the immune and stress hormone responses to 1 h of strenuous rowing exercise, 22 male subjects were randomly assigned to a placebo (PLA, n = 11) or carbohydrate (CHO, n = 11) group. Subjects completed 3 d of modified dietary intake, a standardized pre-exercise meal, and consumed either a carbohydrate beverage (1 g.kg body mass(-1)) or a non-caloric placebo drink before, during, and after a 1 h rowing trial.