Effects of transforming growth factor Beta and insulinlike growth factor 1 on the biomechanical and histologic properties of tissue-engineered cartilage.

Objective: To investigate the histologic and biomechanical properties of rabbit tissue-engineered cartilage exposed to insulinlike growth factor 1 and transforming growth factor beta.

Design: Controlled study.

Subjects: New Zealand white rabbits aged 3 to 4 weeks.