Publications by authors named "Christopher Q Jin"
Front Immunol
September 2022
Article Synopsis
- - Myeloid-derived suppressor cells (MDSCs) are diverse cells that accumulate abnormally from myeloid cell differentiation and primarily function to suppress T cell activity, allowing tumors to evade the immune system.
- - The goal of immunotherapy is to enhance the immune system’s ability to fight tumors, but MDSCs pose a significant challenge by decreasing the effectiveness of these treatments and increasing tumor cell resistance.
- - This review examines the roles and mechanisms of MDSCs in the tumor microenvironment, explores immunotherapy strategies targeting MDSCs, and discusses potential advances in combining these therapies with immune checkpoint blockade for better cancer treatment outcomes.
