Publications by authors named "Christopher Ovenden"

Objective: Radiological prediction of Ki-67 plays a crucial role in determining the clinical outcomes of meningioma patients. The aim of this review is to comprehensively review the literature to synthesize evidence on how accurate radiological prediction of the Ki-67 proliferation index is to determine the Ki-67 index's association with clinical outcomes of meningioma.

Materials And Methods: A narrative synthesis systematic review followed PRISMA guidelines.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the effectiveness of ROTEM sigma, a point-of-care coagulation test, in assessing coagulation in patients with isolated traumatic brain injuries (TBI) compared to traditional lab tests.
  • Out of 36 patients tested, 22% exhibited a hypocoagulable state, which correlated with a higher death rate from head injuries, indicating the prognostic value of ROTEM sigma.
  • ROTEM tests provided faster results than standard tests, demonstrating that ROTEM parameters can quickly and accurately predict the risk of head injury-related death.
View Article and Find Full Text PDF

Background And Purpose: Resuscitation orders describe individual preferences and types of intervention, such as suitability for cardiopulmonary resuscitation (CPR), that may provide benefit in the event of critical deterioration. The purpose of this study was to examine stroke inpatient resuscitation order completion and content.

Methods: This retrospective cohort study examined resuscitation orders in consecutive individuals admitted to a tertiary stroke centre over a 21-month period.

View Article and Find Full Text PDF

Backgrounds: Rapid response team or medical emergency team (MET) calls are typically activated by significant alterations of vital signs in inpatients. However, the clinical significance of a specific criterion, blood pressure elevations, is uncertain.

Objectives: The aim of this study was to evaluate the likelihood ratios associated with MET-activating vital signs, particularly in-patient hypertension, for predicting in-hospital mortality among general medicine inpatients who met MET criteria at any point during admission in a South Australian metropolitan teaching hospital.

View Article and Find Full Text PDF

Background: To determine the quality and reliability of DCR YouTube videos as patient education resources and identify any associated factors predictive of video quality.

Methods: A YouTube search was conducted using the terms "Dacryocystorhinostomy, DCR, surgery" on 12th of January 2022, with the first 50 relevant videos selected for inclusion. For each video, the following was collected: video hyperlink, title, total views, months since the video was posted, video length, total likes/dislikes, authorship (i.

View Article and Find Full Text PDF

Objective: The measurement and recording of vital signs may be impacted by biases, including preferences for even and round numbers. However, other biases, such as variation due to defined numerical boundaries (also known as boundary effects), may be present in vital signs data and have not yet been investigated in a medical setting. We aimed to assess vital signs data for such biases.

View Article and Find Full Text PDF

Objective: The aims of the present study were to determine how renal disease is associated with the time to receive hyperacute stroke care.

Methods: The present study involved a 5-year cohort of all patients admitted to stroke units in South Australia.

Results: In those with pre-existing renal disease there were no significant differences in the time taken to receive a scan, thrombolysis or endovascular thrombectomy.

View Article and Find Full Text PDF

Objective: Decompressive craniectomy (DC) remains a controversial intervention for intracranial hypertension among patients with aneurysmal subarachnoid haemorrhage (aSAH).

Methods: We identified aSAH patients who underwent DC following microsurgical aneurysm repair from a prospectively maintained registry and compared their outcomes with a propensity-matched cohort who did not. Logistic regression was used to identify predictors of undergoing decompressive surgery and post-operative outcome.

View Article and Find Full Text PDF

Objective: Epilepsy surgery is known to be underutilized. Machine learning-natural language processing (ML-NLP) may be able to assist with identifying patients suitable for referral for epilepsy surgery evaluation.

Methods: Data were collected from two tertiary hospitals for patients seen in neurology outpatients for whom the diagnosis of "epilepsy" was mentioned.

View Article and Find Full Text PDF

Background: Sensorineural hearing loss (SNHL) may occur following cardiac surgery. Although preventing post-operative complications is vitally important in cardiac surgery, there are few guidelines regarding this issue. This review aimed to characterize SNHL after cardiac surgery.

View Article and Find Full Text PDF

Background: Anticoagulation can prevent most strokes in individuals with atrial fibrillation (AF); however, many people presenting with stroke and known AF are not anticoagulated. Language barriers and poor health literacy have previously been associated with decreased patient medication adherence. The association between language barriers and initiation of anticoagulation therapy for AF is uncertain.

View Article and Find Full Text PDF

Background: The frequency of oxycodone adverse reactions, subsequent opioid prescription, effect on pain and patient care in general surgery patients are not well known. This study aimed to determine prevalence of documented oxycodone allergy and intolerances (independent variables) in a general surgical cohort, and association with prescribing other analgesics (particularly opioids), subjective pain scores, and length of hospital stay (dependent variables).

Methods: This retrospective cohort study included general surgery patients from two South Australian hospitals between April 2020 and March 2022.

View Article and Find Full Text PDF

Objective: Decompressive craniectomy (DC) following malignant ischaemic stroke is a potentially life-saving procedure. Event rates of ventriculomegaly following DC performed in this setting remain poorly defined. Accordingly, we performed a systematic review to determine the incidence of hydrocephalus and the need for cerebrospinal fluid (CSF) diversion following DC for malignant stroke.

View Article and Find Full Text PDF

Background: This study aimed to examine the accuracy with which multiple natural language processing artificial intelligence models could predict discharge and readmissions after general surgery.

Methods: Natural language processing models were derived and validated to predict discharge within the next 48 hours and 7 days and readmission within 30 days (based on daily ward round notes and discharge summaries, respectively) for general surgery inpatients at 2 South Australian hospitals. Natural language processing models included logistic regression, artificial neural networks, and Bidirectional Encoder Representations from Transformers.

View Article and Find Full Text PDF

Introduction: Readmission is a poor outcome for both patients and healthcare systems. The association of certain sociocultural and demographic characteristics with likelihood of readmission is uncertain in general surgical patients.

Method: A multi-centre retrospective cohort study of consecutive unique individuals who survived to discharge during general surgical admissions was conducted.

View Article and Find Full Text PDF
Article Synopsis
  • This study investigates isopropyl alcohol (IPA) as a potential treatment for nausea, comparing its effectiveness against serotonin (5-HT) antagonists, which are commonly used but not always effective.
  • Researchers conducted a systematic search for randomized controlled trials and included 4 studies with 382 participants, assessing outcomes like nausea severity, duration, and patient satisfaction.
  • Results showed that IPA led to a quicker reduction in nausea and a lower need for additional medications compared to 5-HT antagonists, although overall evidence quality was considered low to very low.
View Article and Find Full Text PDF

Recent literature demonstrates that a learning curve exists for endoscopic pituitary surgery. However, there is significant variability in the way these studies report their outcomes. This study aims to systematically review the literature regarding outcomes for endoscopic pituitary surgery and how this may be related to a surgical learning curve.

View Article and Find Full Text PDF
Article Synopsis
  • Prehabilitation aims to enhance patients' health before surgery to improve surgical outcomes, and a systematic review was conducted to assess its effectiveness within General Surgery based on randomized controlled trials (RCTs).
  • The review included 36 RCTs, mostly from Europe and North America, showing mixed results; while many physical and psychological interventions demonstrated some benefits, the evidence was insufficient for standardized implementation across the discipline.
  • Although prehabilitation interventions showed variability in effectiveness, the potential benefits suggest they should be considered individually rather than as a blanket protocol across all surgical cases.
View Article and Find Full Text PDF

Background: Research guides evidence-based general surgery practice, advocacy, policy and resource allocation, but is seemingly lacking representation from those countries with greatest disease burden and mortality. Accordingly, we conducted a geographic study of publications in the most impactful general surgery journals worldwide.

Methods: The six general surgery journals with the highest 2020 impact factors were selected.

View Article and Find Full Text PDF

Background: The applicability of the vital signs prompting medical emergency response (MER) activation has not previously been examined specifically in a large general surgical cohort. This study aimed to characterize the distribution, and predictive performance, of four vital signs selected based on Australian guidelines (oxygen saturation, respiratory rate, systolic blood pressure and heart rate); with those of the MER activation criteria.

Methods: A retrospective cohort study was conducted including patients admitted under general surgical services of two hospitals in South Australia over 2 years.

View Article and Find Full Text PDF

Introduction: Epilepsy surgery is an underutilised, efficacious management strategy for selected individuals with drug-resistant epilepsy. Natural language processing (NLP) may aid in the identification of patients who are suitable to undergo evaluation for epilepsy surgery. The feasibility of this approach is yet to be determined.

View Article and Find Full Text PDF