Publications by authors named "Christopher O Fakorede"
Article Synopsis
- - Salmonella infections are a major public health concern, particularly in Sub-Saharan Africa, where some non-typhoidal serovars are linked to severe diseases in children; this study focused on identifying and analyzing these resistant and virulent strains in Nigeria.
- - Over a period from December 2017 to May 2019, researchers collected 2,522 samples from humans, animals, and the environment, followed standard microbiological methods for analysis, and conducted antibiotic susceptibility testing and whole genome sequencing (WGS) for deeper insights.
- - The study isolated 48 non-typhoidal Salmonella strains, with varying prevalence rates, identified several serovars, and found that all isolates possessed multiple antibiotic resistance and
Background: Resistance to different antimicrobial classes by Salmonella species has generated a global public health concern. The spread of extended-spectrum β-lactamases (ESBLs) bla gene variants is also increasing. This study aimed to investigate the antibiotic resistance and the carriage of bla and bla as well as the quinolone resistance gene (qnrB19) among Salmonella species from hospitalised patients in Lagos, Nigeria.
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- * It presents estimated seroprevalence rates of brucellosis in Nigeria over the last 20 years, showing 17.6% in humans and 13.3% in animals, with notable geographic differences between northern and southern regions.
- * The study calls for improved detection methods and understanding of brucellosis strains, serving as a resource for researchers and policymakers to better manage the disease.
Background: There is scarce information about the occurrence of extended-spectrum β-lactamases (ESBLs) in a serovar Typhi () from patients with typhoid fever.
Objective: To study the antimicrobial resistance and ESBL encoding genes among isolates in aforesaid patients from Lagos, Nigeria.
Methods: isolates were collected from blood samples of typhoid fever patients from 4 academic medical centers in Lagos, Nigeria.
A systemic review of literatures on human Salmonella enterica serovars in Nigeria (1999-2018).
J Infect Dev Ctries
September 2021
Introduction: Salmonella infections are endemic in Nigeria. There is lack of reliable data on culture-positive Salmonella with national coverage. This systemic review of literatures was undertaken to aggregate data on culture proven cases of human Salmonellae and to determine the prevailing serotypes for disease burden estimations.
View Article and Find Full Text PDFThis study investigated the prevalence of (.) isolates among clinical samples of patients in four medical centers in Lagos, Nigeria and the burden of extended-spectrum beta-lactamases (ESBL) and carbapenem-resistant (CRKP) strains. Different samples (stool, blood, urine, wound swabs and nasal swabs) from 127 patients with suspected Gram-negative infections based on on-site performed Gram-stain from four public hospitals between March and September 2015 were analyzed.
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