Publications by authors named "Christopher O Anele"

Cerebral venous sinus thrombosis (CVST) is an uncommon and underreported neurological condition. This condition has varied aetiologies, clinical manifestations, and significant sequelae if left untreated. We report the case of a 10-year-old male with fever, altered sensorium, cranial nerve neuropathies, and left hemiplegia.

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Article Synopsis
  • Adult-onset aqueductal stenosis (AOAS) is a rare cause of hydrocephalus in adults, and its understanding, especially in Africa, is limited—this study focused on its presentation and outcomes in Nigeria from 2008 to 2023.* -
  • The research included 8 patients (7 males, 1 female) aged 18 to 50, primarily presenting with headaches and visual problems, with some experiencing additional symptoms like cognitive deficits and cerebrospinal fluid leaks.* -
  • Ventriculoperitoneal shunt surgery was performed on most patients, leading to favorable outcomes, highlighting the importance of diagnosing AOAS early to prevent severe complications like vision loss.*
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Purpose: A congenital encephalocele is the herniation of intracranial contents through skull defects of various sizes. Depending on the site, content, and size, it is associated with significant morbidity and mortality in children. There is a paucity of recent and comprehensive local clinical data regarding this anomaly.

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An acute ischemic stroke, though carrying the risk of debilitating complications, is a preventable and treatable disease. Thrombolysis and endovascular thrombectomy are important components of its management. However, various challenges in resource-poor countries like Nigeria and other developing nations pose a great limitation in the timely intervention of ischemic stroke treatment.

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Hydrocephalus is a very common brain disorder affecting both children and adult populations. Its global burden has been well documented in the literature, and its management is not without challenges and complications, especially in low-income countries. This study aims at reviewing the management of hydrocephalus in a tertiary hospital in Nigeria and illustrating two cases managed with peculiar challenges.

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Background: Central nervous system tumors are a complex heterogeneous group of neoplasm comprising both benign and malignant tumors with varied patterns in clinical picture and histologic profile. There have been some similarities and differences seen in the pattern of clinicopathological profile worldwide, however, there is a paucity of study to show the pattern in Nigeria.

Aim: This study aimed at describing the clinical and histopathological pattern of central nervous system tumors in our institution.

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