Publications by authors named "Christopher Mirfin"
Article Synopsis
- This study focuses on improving RF shimming for single-voxel MRS at ultrahigh field by creating calibration-free RF shims that can be used for any participant and effectively target specific brain regions.
- The RF shims were optimized using data from 11 subjects and focused on areas like the occipital cortex and hippocampus, revealing no significant difference in performance compared to tailored shims.
- Results showed that calibration-free shims maintained strong signal quality while reducing specific-absorption-rate deposition, suggesting they could enhance imaging efficiency without the need for complex mapping procedures.
Diffusion MRI is an exquisitely sensitive probe of tissue microstructure, and is currently the only non-invasive measure of the brain's fibre architecture. As this technique becomes more sophisticated and microstructurally informative, there is increasing value in comparing diffusion MRI with microscopic imaging in the same tissue samples. This study compared estimates of fibre orientation dispersion in white matter derived from diffusion MRI to reference measures of dispersion obtained from polarized light imaging and histology.
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