Publications by authors named "Christopher Meulengracht"
Article Synopsis
- A recent study examined the effects of a 12-week pain-guided activity modification program on elite athletes with early Achilles or patellar tendinopathy, showing clinical improvements despite unchanged tendon structure.
- The research involved 65 athletes divided into three groups based on symptom duration (0-3 months) and assessed various clinical and imaging outcomes at the beginning and end of the study.
- Key findings revealed that while athletes reported reductions in pain and improvement in function, the structural aspects of their tendons remained largely the same throughout the 12-week period, indicating that clinical recovery does not necessarily correlate with physical changes in tendon morphology.
Muscle fibre denervation and declining numbers of muscle stem (satellite) cells are defining characteristics of ageing skeletal muscle. The aim of this study was to investigate the potential for lifelong recreational exercise to offset muscle fibre denervation and compromised satellite cell content and function, both at rest and under challenged conditions. Sixteen elderly lifelong recreational exercisers (LLEX) were studied alongside groups of age-matched sedentary (SED) and young subjects.
View Article and Find Full Text PDFBackground: Glioblastoma ranks among the most lethal cancers, with current therapies offering only palliation. Paracrine vascular endothelial growth factor (VEGF) signaling has been targeted using anti-angiogenic agents, whereas autocrine VEGF/VEGF receptor 2 (VEGFR2) signaling is poorly understood. Bevacizumab resistance of VEGFR2-expressing glioblastoma cells prompted interrogation of autocrine VEGF-C/VEGFR2 signaling in glioblastoma.
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