Refined methodology for quantifying virulence using .

Larvae of (the greater wax moth) are being increasingly used as a model to study microbial pathogenesis. In this model, bacterial virulence is typically measured by determining the 50% lethal dose (LD) of a bacterial strain or mutant. The use of to study pathogenesis, however, is challenging because of the extreme sensitivity of larvae to this bacterium.

Klebsiella pneumoniae clinical isolates with features of both multidrug-resistance and hypervirulence have unexpectedly low virulence.

Klebsiella pneumoniae has been classified into two types, classical K. pneumoniae (cKP) and hypervirulent K. pneumoniae (hvKP).

Genome-wide screens reveal shared and strain-specific genes that facilitate enteric colonization by .

is a common cause of difficult-to-treat infections due to its propensity to express resistance to many antibiotics. For example, carbapenem-resistant has been named an urgent threat by the United States Centers for Disease Control and Prevention. Gastrointestinal colonization in patients with has been linked to subsequent infection, making it a key process to control in the prevention of multidrug-resistant infections.