An Amplitude-Integrated EEG Evaluation of Neonatal Opioid Withdrawal Syndrome.

Objective: Infants with neonatal opioid withdrawal syndrome (NOWS) have disrupted neurobehavior that requires hospitalization and treatment. This article aimed to evaluate electroencephalography (EEG) abnormalities using amplitude-integrated EEG (aEEG) in NOWS.

Study Design: Eighteen term born infants with NOWS were recruited prospectively for an observational pilot study.

Poverty and Excess Length of Hospital Stay in Neonatal Opioid Withdrawal Syndrome.

Objectives: To study the impact of sociodemographic factors on length of stay (LOS) for infants with neonatal opioid withdrawal syndrome (NOWS) secondary to fetal opioid exposure.

Methods: In this retrospective cohort study, we included term infants with NOWS, excluding those with other significant medical issues. Comprehensive clinical and sociodemographic data were collected.

Early red cell transfusion is associated with development of severe retinopathy of prematurity.

Objective: To evaluate the association between early (within 10 d) pRBC transfusion and the development of severe ROP.

Study Design And Methods: This was a single-center retrospective study. Inclusion criteria were preterm infants born ≤32 weeks gestation or weighing ≤1500 g.

Cytokine and chemokine profiles in multiple myeloma; significance of stromal interaction and correlation of IL-8 production with disease progression.

Multiple myeloma (MM) is a product of interactions between tumor plasma cells and multiple cell types native to the bone marrow (BM). We have used antibody array technology to examine the proteins produced by BM stromal cells in response to stimulation by BM taken from patients diagnosed with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and MM. We observed increased production of the chemokine IL-8 by stromal cells co-cultured with supernatants from bone marrow cells of patients with active myeloma.