Functional comparison of pacifiers using finite element analysis.

Background: Pacifiers have been shown to affect maxillary growth related to the anatomic structure of the palate and forces placed upon it during sucking. This study compares and evaluates the mechanical behavior of pacifiers of different design and size (i.e.

Computational simulation of pacifier deformation and interaction with the palate.

Objectives: The objective of this study is to demonstrate that computational finite element models can be used to reliably simulate dynamic interaction between a pacifier, the palate, and the tongue during nonnutritive sucking (NNS). The interactions can be quantified by the results of finite element analyses which include deformation, strain, stress, contact force, and contact area.

Materials And Methods: A finite element model was created based upon CAD solid models of an infant pacifier and palate.

A 3D-Printed Patient-Specific Phantom for External Beam Radiation Therapy of Prostate Cancer.

This paper presents the design evolution, fabrication, and testing of a novel patient and organ-specific, 3D printed phantom for external beam radiation therapy of prostate cancer. In contrast to those found in current practice, this phantom can be used to plan and validate treatment tailored to an individual patient. It contains a model of the prostate gland with a dominant intraprostatic lesion, seminal vesicles, urethra, ejaculatory duct, neurovascular bundles, rectal wall, and penile bulb generated from a series of combined T2-weighted/dynamic contrast-enhanced magnetic resonance images.

Epidermal Growth Factor Receptor-Specific Nanoprobe Biodistribution in Mouse Models.

Nanotechnology offers a targeted approach to both imaging and treatment of cancer, the leading cause of death worldwide. Previous studies have found that nanoparticles with a wide variety of coatings initiate an immune response leading to sequestration in the liver and spleen. In an effort to find a nanoparticle platform which does not elicit an immune response, we created 43 nm and 44 nm of gold and silver nanoparticles coated with biomolecules normally produced by the body, α-lipoic acid and the epidermal growth factor (EGF), and have used mass spectroscopy to determine their biodistribution in mouse models, 24 h after tail vein injection.

Some Historical Treatments should not be Forgotten: A Review of Cast Wedging and A Trick to Normalize Non-Standardized Digital X-rays.

Introduction: Cast wedging is a simple and reproducible method of manipulating a sub-optimally reduced fracture producing a correction and a final alignment that is amenable to definitive closed treatment. Multiple successful techniques have been previously described in the literature (opening wedge, closing wedge and combination).

Technical Note: We present a simple reproducible method of templating and executing a proper cast wedging technique using digital imaging systems that are not controlled for magnification with an illustrative case.

Management of Cannulated Screw Failure and Recurrent SCFE Displacement - Case Report.

Introduction: SCFE occurs in 10 per 100,000 in some regions of the United States with the incidence continuing to increase. Percutaneous screw fixation is a well-accepted treatment for this disorder for over 20 years but management of complications is not well elucidated in the literature.

Case Report: We describe a case where a traumatic unstable SCFE that was initially treated with closed reduction and fixation with a single transphyseal screw went on to hardware failure with recurrence of the deformity.

Fracture through a Harris growth arrest line: a case report.

Fractures occur when bone is overloaded and mechanical failure occurs with the fracture propagating along the lines of least resistance. We report the case of a 6-year-old boy who sustained a nondisplaced distal third tibial shaft fracture through a Harris growth arrest line of increased osseous density due to low-energy blunt trauma. This case is used as an opportunity to review the literature on Harris growth arrest lines and discuss a fracture pattern that has not been previously described in the literature.