Development and implementation of a cohort review for latent tuberculosis infection.

The Centers for Disease Control and Prevention (CDC) recommends that, in low-incidence settings for tuberculosis (TB), health departments periodically review their cases of latent TB infection (LTBI). The objective of this study was to evaluate the design and implementation of an LTBI cohort review that can be used to assess program performance. The methods used for the LTBI cohort review were developed and modified from those described previously by the CDC for TB disease.

Physiological and neurobehavioral effects of cholinesterase inhibition in healthy adults.

Introduction: Based on common pharmacodynamic mechanisms, recent efforts to develop second generation alternatives for organophosphate (OP) prophylaxis have expanded to include cholinesterase (ChE) inhibiting compounds traditionally approved for use in the treatment of Alzheimer's disease (AD). The primary purpose of this study was to determine the extent to which low-dose huperzine A, galantamine, or donepezil selectively inhibited acetylcholinesterase (AChE) versus butyrylcholinesterase (BChE) activity in healthy adults and whether such inhibition impacted neurobehavioral performance.

Methods: In addition to hourly red blood cell cholinesterase sampling, neurobehavioral function was assessed before and after a single oral dose of huperzine A (100 or 200 μg), galantamine (4 or 8 mg), donepezil (2.

Using the tuberculosis cohort review to evaluate and improve the U.S. Army's tuberculosis control program.

The challenges of tuberculosis (TB) control in the U.S. military are similar to those in other low-incidence populations; in addition, the U.

Tuberculosis trends in the U.S. Armed Forces, active component, 1998-2012.

Members of the Armed Forces represent a segment of the U.S. population that may be at increased risk for tuberculosis (TB) infection, disease, and transmission due to overseas service in endemic areas and residence in congregate settings.

Tuberculosis among nonimmigrant visitors to US Military installations.

Background: Nonimmigrant visitors are not required to be evaluated for tuberculosis (TB) before entering the country. Little literature exists describing the challenges of TB control among this demographic. This report reviews the challenges in managing TB in this population on U.