Computed tomography-based radiomic markers are independent prognosticators of survival in advanced laryngeal cancer: a pilot study.

Objective: Advanced laryngeal cancers are clinically complex; there is a paucity of modern decision-making models to guide tumour-specific management. This pilot study aims to identify computed tomography-based radiomic features that may predict survival and enhance prognostication.

Methods: Pre-biopsy, contrast-enhanced computed tomography scans were assembled from a retrospective cohort ( = 72) with advanced laryngeal cancers (T3 and T4).

Assessing the impact of 3D image segmentation workshops on anatomical education and image interpretation: A prospective pilot study.

Three-dimensional (3D) segmentation, a process involving digitally marking anatomical structures on cross-sectional images such as computed tomography (CT), and 3D printing (3DP) are being increasingly utilized in medical education. Exposure to this technology within medical schools and hospitals remains limited in the United Kingdom. M3dicube UK, a national medical student, and junior doctor-led 3DP interest group piloted a 3D image segmentation workshop to gauge the impact of incorporating 3D segmentation technology on anatomical education.

Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse.

Background: Less than 5% of medulloblastoma (MB) patients survive following failure of contemporary radiation-based therapies. Understanding the molecular drivers of medulloblastoma relapse (rMB) will be essential to improve outcomes. Initial genome-wide investigations have suggested significant genetic divergence of the relapsed disease.

The Effect of the 2019 Novel Coronavirus Pandemic on Stroke and TIA Patient Admissions: Perspectives and Risk Factors.

Background: The 2019 novel coronavirus pandemic has generated concern from stroke specialist centres across the globe. Reductions in stroke admissions have been reported, despite many expecting an increase due to the pro-thrombotic nature of 2019 novel coronavirus.

Aims: To assess the impact of the pandemic and subsequent lockdown on stroke admissions and transient ischaemic attack referrals at the Royal Victoria Infirmary, Newcastle-Upon-Tyne, and additionally on patient behaviours affecting modifiable risk factors or perspectives related to accessing healthcare.

The role of 3D printing in anatomy education and surgical training: A narrative review.

This article was migrated. The article was marked as recommended. Recent expansions in the development and availability of three-dimensional printing (3Dp) have led to the uptake of this valuable and effective technology within the modern context of medical education.

Ca(2+) mobilization in cumulus cells: role in oocyte maturation and acrosome reaction.

The cumulus mass is a group of cells surrounding the oocyte. Cumulus cells are known to play a role in a number of reproductive events including oocyte maturation and acrosome reaction. Calcium mobilization in cumulus cells has been implicated in the process of oocyte maturation and acrosome reaction; however, its exact role remains elusive.