Development of a Model System to Evaluate Local Recurrence in Osteosarcoma and Assessment of the Effects of Bone Morphogenetic Protein-2.

Purpose: It is increasingly relevant to better define what constitutes an adequate surgical margin in an effort to improve reconstructive longevity and functional outcomes following osteosarcoma surgery. In addition, nonunion remains a challenging problem in some patients following allograft reconstruction. Bone morphogenetic protein-2 (BMP-2) could enhance osseous union, but has been historically avoided due to concerns that it may promote tumor recurrence.

Telescopic mating technique for bulk allograft reconstruction.

Bulk allograft reconstruction plays an important role in limb-salvage reconstructive surgery but is complicated by nonunion in up to one-third of cases. Because allograft-host healing is mediated via creeping substitution, intimate bone contact is desirable. Intraoperative assessment and optimization of the allograft-host junction site using a conventional transverse osteotomy is challenging and may result in slight gapping.

Outcomes after the arthroscopic treatment of femoroacetabular impingement in a mixed group of high-level athletes.

Background: Femoroacetabular impingement has become more widely recognized in the athletic patient population. The purpose of the present study was to review the clinical outcome after arthroscopic treatment of femoroacetabular impingement in a mixed population of high-level athletes.

Hypothesis: Arthroscopic treatment of femoroacetabular impingement results in significant improvement in clinical outcome and a high rate of return to play.