The effect of high fat, high sugar, and combined high fat-high sugar diets on spatial learning and memory in rodents: A meta-analysis.

Evidence from human and animal studies suggests that high-energy diets impair cognitive function. However, the conditions for such impairments are unclear as studies have differed in the type and duration of diet exposure as well as in the tasks used to assess deficits in cognition. Here, we focused on hippocampal-dependent tasks.