Publications by authors named "Christopher J Schutta"
Article Synopsis
- Researchers explored the use of Modified Vaccinia virus Ankara-Bavarian Nordic (MVA-BN®) to develop recombinant vaccines for foot-and-mouth disease (FMD) targeting newly emerging strains of the FMD virus (FMDV).
- The study involved expressing different variants of the FMDV 3C protease to enhance vaccine safety while still effectively producing the necessary FMDV antigens.
- Two MVA-BN FMD constructs were found to be safe and effective in cattle, achieving full protection against clinical FMD and the virus, while also allowing for easy differentiation between vaccinated and infected animals.
