Publications by authors named "Christopher J Rudge"
Article Synopsis
- Living donor kidney transplants generally result in better outcomes than deceased donor transplants, but results can vary significantly based on several factors.
- An analysis of over 3,000 cases revealed that while patient survival is higher for related donors, graft survival is better for unrelated donors, although these differences diminished once other influencing factors were considered.
- Key findings indicate that older donor age negatively impacts patient survival and that factors like recipient diabetes and gender also play a role, but the expected impact of HLA mismatches was not observed.
Patients waiting more than 3 years for a renal transplant were ranked according to our novel Bristol and Region Allocation by Non-heart beating Donor Score (BRANDS). One kidney from 40 non-heart beating donors was allocated to the highest BRANDS long-waiter and the other kidney allocated according to the UK National Allocation Scheme (NAS). The scheme reduced the number of patients waiting more than 3 years by 20%.
View Article and Find Full Text PDFThe national scheme currently used for the allocation of cadaver kidneys in the United Kingdom includes factors demonstrated to improve transplant outcome and promote equity in organ allocation. Introduced in 1998, the scheme is based on human leukocyte antigen matching, gives priority to children and highly sensitized patients, and incorporates features to assist transplantation in patients who are difficult to match. The scheme is open and transparent and subject to continuous audit and review to address any inequities in access to transplant that become apparent.
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