Publications by authors named "Christopher J Dennis"
Article Synopsis
- Amyloid fibrils are protein structures associated with neurodegenerative diseases, and they are important for creating specific ligands for medical imaging and treatment.
- Solid-state NMR (SSNMR) is a technique used to analyze these fibrils, but traditional methods require a lot of manual data analysis, which slows down the process.
- The study presents a new automated method using probabilistic assignment and symmetry in software, which successfully determined the structure of an α-synuclein fibril linked to Parkinson's, significantly reducing the time and manual effort needed for structure analysis.
Background: When urgently intubating patient in the burn intensive care unit (BICU), various induction agents, including propofol, are utilized that may induce hemodynamic instability.
Methods: A retrospective review was performed of consecutive critically ill burn patients who underwent urgent endotracheal intubation in BICU. Basic burn-related demographic data, indication for intubation, and induction agents utilized were recorded.