Publications by authors named "Christopher Gebert"

The purpose of the study was to examine the morphology and biomechanical characteristics of in vivo cultured tissue-engineered human septal cartilage as a prospective autogenous transplant material for subcutaneous implantation in reconstructive procedures. Chondrocytes were enzymatically isolated from human septal cartilage biopsies. The cell number was expanded in monolayer culture.

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Functional organ or tissue failure is one of the most frequent, devastating and costly problems in modern health care. The field of tissue engineering has tremendous potential for developing new functional tissue. In reconstructive surgery, cartilage engineering could be a serious alternative to the established method of autologous cartilage transplantation.

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Article Synopsis
  • Current surgical techniques for ear reconstruction using natural tissue often lead to unsatisfactory cosmetic results due to the limitations of conventional rib cartilage shaping.
  • Tissue engineering offers an innovative solution by enabling the creation of precise cartilage implants without the drawbacks of donor site complications.
  • In this study, researchers successfully developed auricular-shaped cartilage implants using human cells and bioresorbable scaffolds, demonstrating effective tissue formation and stability over time in preclinical experiments.
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