A Deep Learning Approach to Photoacoustic Wavefront Localization in Deep-Tissue Medium.

Optical photons undergo strong scattering when propagating beyond 1-mm deep inside biological tissue. Finding the origin of these diffused optical wavefronts is a challenging task. Breaking through the optical diffusion limit, photoacoustic (PA) imaging (PAI) provides high-resolution and label-free images of human vasculature with high contrast due to the optical absorption of hemoglobin.

Light-Emitting-Diode-Based Multispectral Photoacoustic Computed Tomography System.

Photoacoustic computed tomography (PACT) has been widely explored for non-ionizing functional and molecular imaging of humans and small animals. In order for light to penetrate deep inside tissue, a bulky and high-cost tunable laser is typically used. Light-emitting diodes (LEDs) have recently emerged as cost-effective and portable alternative illumination sources for photoacoustic imaging.

A Single Simulation Platform for Hybrid Photoacoustic and RF-Acoustic Computed Tomography.

In recent years, multimodal thermoacoustic imaging has demonstrated superior imaging quality compared to other emerging modalities. It provides functional and molecular information, arising due to electromagnetic absorption contrast, at ultrasonic resolution using inexpensive and non-ionizing imaging methods. The development of optical- as well as radio frequency (RF)-induced thermoacoustic imaging systems would benefit from reliable numerical simulations.