Publications by authors named "Christopher Claudius Maximilian Neumann"
Pancreatic ductal adenocarcinoma (PDAC) remains a particularly aggressive disease with few effective treatments. The PDAC tumor immune microenvironment (TIME) is known to be immune suppressive. Oncolytic viruses can increase tumor immunogenicity via immunogenic cell death (ICD).
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- Pancreatic cancer is a major cause of death, and this study investigates how body composition measured through CT scans can predict survival rates using AI techniques.
- The research included 103 patients and highlighted that surgical treatment significantly improves 1-year, 2-year, and 3-year survival rates, while sarcopenia (muscle loss) and visceral fat also play critical roles in determining survival outcomes.
- The findings showed that sarcopenia negatively impacts survival more in surgical patients compared to nonsurgical ones, indicating that assessing muscle mass and fat distribution can help guide treatment decisions and predict patient outcomes.