Publications by authors named "Christopher Celano"

Background: Following acute coronary syndrome (ACS), up to 40% of patients report elevated depressive symptoms which is associated with a two-fold increase in mortality risk due to behavioral and biological mechanisms. Mindfulness-Based Cognitive Therapy (MBCT) delivered via synchronous group videoconferencing could help reduce depressive symptoms.

Objective: To guide MBCT adaptation for ACS patients for a future clinical trial, this qualitative study aimed to explore ACS patients' (1) symptoms after ACS, (2) needs for behavioral health treatment, (3) perspectives on mindfulness intervention and group videoconference delivery, and (4) willingness to self-collect dried blood spots in a research study.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the psychological challenges faced by survivors of allogeneic hematopoietic stem cell transplantation (HSCT) and tests a telephone-based positive psychology intervention called PATH to improve their well-being.
  • PATH involved 9 weekly phone sessions emphasizing gratitude, personal strengths, and finding meaning in life, and aimed for high participant enrollment and session completion.
  • Results showed promising improvements in gratitude, anxiety, physical function, and other psychological factors among those who participated in PATH compared to those receiving usual care.
View Article and Find Full Text PDF

Background: Depression affects 20-30% of individuals with heart failure (HF), and it is associated with worse health outcomes independent of disease severity. One potential explanation is the adverse impact of depression on HF patients' adherence to the health behaviors needed to self-manage their condition. The aim of this study is to identify characteristics associated with lower adherence in this population, which could help to recognize individuals at higher risk and eventually tailor health behavior interventions to their needs.

View Article and Find Full Text PDF

Objective: Postoperative delirium (POD) is a common complication of cardiac surgery that is associated with higher morbidity, longer hospital stay, cognitive decline, and mortality. Preoperative assessments may help to identify patients´ POD risk. However, a standardized screening assessment for POD risk has not been established.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated a 12-week text message intervention aimed at improving health behaviors and psychological well-being in individuals with multiple cardiac risk conditions.
  • The intervention was found to be highly feasible and accepted, with 99.3% successful message delivery and a mean utility rating of 7.4/10.
  • Results showed small improvements in physical activity, optimism, anxiety, self-efficacy, and physical function compared to usual care, indicating the potential for this approach in clinical settings.
View Article and Find Full Text PDF

Background: Patients experiencing significant agitation or perceptual disturbances related to delirium in an intensive care setting may benefit from short-term treatment with an antipsychotic medication. Some antipsychotic medications may prolong the QTc interval, which increases the risk of potentially fatal ventricular arrhythmias. In this targeted review, we describe the evidence regarding the relationships between antipsychotic medications and QTc prolongation and practical methods for monitoring the QTc interval and mitigating arrhythmia risk.

View Article and Find Full Text PDF

Background: There is currently an increasing recognition of and focus on structural and institutional racism and its impacts on health disparities. In psychiatry and mental health, research has focused on racial and ethnic disparities in the availability and utilization of mental health services, care in emergency departments, and inpatient psychiatric services. Little is known about disparities in care on general hospital psychiatry consultation-liaison (CL) services.

View Article and Find Full Text PDF

Objective: Atrial fibrillation (AF) is associated with impaired health-related quality of life (HRQoL), an increased risk of morbidity, and mortality. Traditional AF-related outcomes (e.g.

View Article and Find Full Text PDF

Positive thoughts and emotions contribute to overall psychological health in diverse medical populations, including patients undergoing HSCT. However, few studies have described positive psychological well-being (eg, optimism, gratitude, flourishing) in patients undergoing HSCT using well-established, validated patient-reported outcome measures. We conducted cross-sectional secondary analyses of baseline data in 156 patients at 100 days post-HSCT enrolled in a randomized controlled trial of a psychological intervention (ClinicalTrials.

View Article and Find Full Text PDF
Article Synopsis
  • Patients undergoing allogeneic hematopoietic stem cell transplantation often face low levels of positive psychological well-being (PPWB), and there are few targeted interventions to address this issue.
  • The study involves a randomized controlled trial (RCT) assessing a nine-week positive psychology intervention (PATH) designed for HSCT survivors, focusing on improving their emotional well-being and quality of life.
  • The primary goals are to evaluate the intervention's feasibility and acceptability, while also exploring its potential benefits in reducing anxiety and enhancing overall quality of life among participants.
View Article and Find Full Text PDF
Article Synopsis
  • Peer support can help patients with kidney disease feel better and stick to their treatments, but we don't know a lot about how effective these programs are.
  • Researchers looked at 12 studies involving nearly 3000 patients to see how peer support affects health outcomes like mental well-being and care engagement.
  • Although some studies showed peer support is helpful, more research is needed to understand how to use these programs better in hospitals and clinics.
View Article and Find Full Text PDF

Background: Cardiovascular disease remains the leading worldwide cause of mortality. There has been increased awareness of the impact of psychological health on cardiovascular disease. In particular, major depression has been linked to increased all-cause mortality, development of cardiovascular disease, and worse outcomes in those with existing cardiovascular disease.

View Article and Find Full Text PDF

Positive psychological well-being is prospectively associated with superior health outcomes. Positive psychology interventions have promise as a potentially feasible and effective means of increasing well-being and health in those with medical illness, and several initial studies have shown the potential of such programs in medical populations. At the same time, numerous key issues in the existing positive psychology literature must be addressed to ensure that these interventions are optimally effective.

View Article and Find Full Text PDF

Background: Heart failure (HF) is associated with an elevated risk of morbidity, mortality, hospitalization, and impaired quality of life. One potential contributor to these poor outcomes is depression. Yet the effectiveness of treatments for depression in patients with HF is mixed, perhaps due to the heterogeneity of depression.

View Article and Find Full Text PDF
Article Synopsis
  • Older individuals often experience co-morbidities and frailty before elective surgeries, which can lead to complications; prehabilitation seeks to enhance their preoperative health.
  • A scoping review identified 36 studies from between August 2012 and August 2022, focusing on the effectiveness of various prehabilitation methods, primarily exercise therapy.
  • Evidence suggests that prehabilitation, particularly multimodal programs, may improve postoperative recovery for older, frail patients undergoing surgeries like hip or knee replacements and cancer-related operations, though more robust studies are needed to confirm these benefits.
View Article and Find Full Text PDF

Objective: Psychological factors (e.g., depression, anxiety) are known to contribute to the development and maintenance of irritable bowel syndrome (IBS).

View Article and Find Full Text PDF

Background: Though a growing body of research suggests that greater positive psychological well-being in irritable bowel syndrome (IBS) may be protective, existing brain-gut behavior therapies primarily target negative psychological factors. Little is known about how positive psychological factors in IBS relate to IBS symptoms, health-related quality of life (HRQoL), or adherence to key health behaviors, such as physical activity and diet modification. Accordingly, per the ORBIT model of behavioral treatment development for chronic diseases, we explored potential connections between psychological constructs and IBS symptoms, health behavior engagement (physical activity and dietary modification), and HRQoL in a qualitative study to inform the development of a novel brain-gut behavior therapy.

View Article and Find Full Text PDF

Objective: We conducted an updated, comprehensive, and contemporary systematic review to examine the efficacy of existing pharmacologic agents employed for management of delirium symptoms among hospitalized adults.

Methods: Searches of PubMed, Scopus, Embase, and Cochrane Library databases from inception to May 2021 were performed to identify studies investigating efficacy of pharmacologic agents for management of delirium.

Results: Of 11,424 articles obtained from searches, a total of 33 articles (N = 3030 participants) of randomized or non-randomized trials, in which pharmacologic treatment was compared to active comparator, placebo, or no treatment, met all criteria and were included in this review.

View Article and Find Full Text PDF

Background: Little is known about the impact of psychiatric comorbidity on pharmacologic treatment outcomes, including neuromodulators (medications targeting the gut-brain axis), among adult patients with disorders of gut-brain interaction (DGBI). Accordingly, we aimed to examine associations between psychiatric comorbidity and DGBI pharmacologic treatment outcomes.

Methods: In a retrospective study of consecutively referred new patients (N = 410; ages 18-90; 73% female) to a tertiary neurogastroenterology clinic in 2016 with follow-up through 2018, relationships between psychiatric illness (any psychiatric illness, anxiety disorders, depressive disorders) and pharmacologic treatment selection (any medication, neuromodulating medication) and treatment outcomes, respectively, were examined using multivariable logistic regression, adjusting for demographics, gastrointestinal (GI) diagnoses, and pre-existing neuromodulator use.

View Article and Find Full Text PDF

Objective: In Germany, multimodal psychosomatic inpatient treatment can be initiated for patients with substantial mental disorders (e.g., depression, anxiety, somatoform disorders) and comorbid physical disease.

View Article and Find Full Text PDF

Positive psychological interventions (PPIs), which aim to cultivate psychological well-being, have the potential to improve health behavior adherence. This systematic review summarized the existing literature on PPI studies with a health behavior outcome to examine study methodology, quality, and efficacy. Of the 27 identified studies, 20 measured physical activity, eight measured medication adherence, seven measured diet, and three measured smoking (eight targeted multiple behaviors).

View Article and Find Full Text PDF

Background: Physical activity is critical for preventing and treating Type 2 diabetes (T2D). It is important to identify different profiles of physical activity change among those participating in behavioral interventions to optimize intervention-person fit.

Methods: This study analyzes longitudinal trajectories of change in moderate-to-vigorous physical activity (MVPA) in a positive psychology (PP) and motivational interviewing (MI) intervention for T2D, using latent growth curve modeling (LGCM).

View Article and Find Full Text PDF