Publications by authors named "Christopher Blosch"
Article Synopsis
- Maintaining physical fitness is crucial for adults with cystic fibrosis (pwCF), but there is limited data on how new therapies like ETI affect their fitness levels over time.
- A study tracked 28 adult pwCF for about 5.6 years, measuring various physical fitness components and health indicators like BMI and FEV1, finding significant improvements in BMI and some health-related fitness measures after starting ETI therapy.
- While ETI therapy showed some positive effects, the overall impact on fitness was small, suggesting that other factors also play a role in achieving high physical fitness in pwCF.
Article Synopsis
- Habitual physical activity and exercise training are crucial for improving health and quality of life in people with cystic fibrosis (pwCF), particularly with the advent of new CFTR modulator therapies like Elexacaftor/Tezacaftor/Ivacaftor (ETI).
- A study was conducted to evaluate the effects of ETI on habitual physical activity, measuring steps per day and intensity among adult pwCF over time, with a focus on data collected during the post-pandemic period.
- Results showed that pwCF on ETI increased daily steps by 25%, while those not receiving ETI saw a slight decline; however, changes in lung function were significant for those on
Background: The influence of habitual physical activity and exercise capacity on health-related quality of life (HRQoL) in people with cystic fibrosis (pwCF) is poorly characterized. This study investigated the influence of habitual physical activity, exercise capacity, lung function, and body mass index (BMI) on HRQoL in adolescent and adult pwCF.
Method: Subjects were fitted with an accelerometer to determine habitual physical activity (steps/day), including time spent at different intensities, for up to 4 weeks.
Article Synopsis
- The study examines the impact of the Elexacaftor/Tezacaftor/Ivacaftor (ETI) therapy on health-related quality of life (HRQoL) in adults with cystic fibrosis (pwCF) over a period of about 5.6 years, comparing those who received ETI to those who did not.
- It found that ETI significantly improved several HRQoL domains, while pwCF not on ETI saw little improvement in psychosocial factors and decline in physical health over time.
- The findings suggest ETI therapy enhances both HRQoL and clinical outcomes, but disease progression appears to affect physical health more negatively than psychological aspects; however
Exercise programs for young people after cancer are not part of regular oncological care. This study describes and evaluates a regional outdoor exercise program and presents data with regard to the promoting and inhibiting factors for participation among pediatric cancer survivors. Exercise options, number of participants, and the cohort were evaluated descriptively for one year.
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- The study aimed to evaluate a monitored exercise program's impact on aerobic fitness in children with cystic fibrosis (CF), involving six participants aged 6 to 14.
- After 12 months, aerobic fitness measures (VO2peak and Wpeak) showed slight improvements during the monitoring phase but remained stable post-monitoring.
- The findings suggest that continuous exercise monitoring may enhance physical fitness and encourage ongoing physical activity in CF children, highlighting the importance of support from exercise therapists.
Objectives: The aim of this study was to examine the concurrent validity of the HUMAC Balance System (HBS) and Balance Trainer BTG4 (BTG) in comparison to a laboratory-grade force platform (FP) for postural control (PC) and vertical jump performance (VJP) assessment. In addition, reliability of the three devices was measured for PC.
Methods: Overall 22 participants (age = 37.