An Examination of the Diagnostic Utility of Ubiquitin-Specific Peptidase 6 (USP6) Rearrangement in Differentiating Nodular Fasciitis From Inflammatory Myofibroblastic Tumor: A Case Report.

Nodular fasciitis (NF) is a benign yet diagnostically challenging mesenchymal myofibroblastic proliferation that often mimics the histological features of inflammatory myofibroblastic tumors (IMTs) and soft tissue sarcomas. The overlap in histopathological appearance, compounded by the variability in immunohistochemical (IHC) staining, frequently leads to diagnostic uncertainty. In this report, we present a case of a rapidly expanding lesion on the left medial mandible, ultimately diagnosed as NF.

Identifying critical quality metrics in Mohs Surgery: A national expert consensus process.

Background: Amid a movement toward value-based healthcare, increasing emphasis has been placed on outcomes and cost of medical services. To define and demonstrate the quality of services provided by Mohs surgeons, it is important to identify and understand the key aspects of Mohs micrographic surgery (MMS) that contribute to excellence in patient care.

Objective: The purpose of this study is to develop and identify a comprehensive list of metrics in an initial effort to define excellence in MMS.

Multicenter, prospective feasibility study of Nano-Pulse Stimulation™ technology for the treatment of both nodular and superficial low-risk basal cell carcinoma.

Background: Nano-Pulse Stimulation™ (NPS™) therapy is a new, non-thermal bioelectric modality that applies ultrashort pulses of electric energy to trigger regulated cell death (RCD) in treated tissues. Instead of initiating necrosis by heating or freezing, NPS therapy permeabilizes intracellular organelles to activate the cell's own self-destruct pathway of programmed or regulated cell death. Unlike cryotherapeutic procedures that can both damage structural tissues and diffuse into the periphery beyond the margins of the lesion, NPS therapy only affects cells within the treated zone leaving surrounding tissue and acellular components unaffected.

Conservative thickness layers in Mohs micrographic surgery.

Background: Mohs micrographic surgery (MMS) is used to treat cutaneous malignancies in locations to maximize tissue sparing. The authors' aim is to demonstrate the utility of conservative thickness layers (CTL) in MMS and review patient and tumor characteristics and the potential anatomic locations where this technique may be most useful.

Methods: We performed a retrospective chart review of patients with tumors treated with CTL in MMS of 339 tumors, recording patient demographics, tumor characteristics, MMS stages for clearance, repairs, complications, and follow-up.

Understanding Mohs Micrographic Surgery: A Review and Practical Guide for the Nondermatologist.

The incidence and diagnosis of cutaneous malignancies are steadily rising. In addition, with the aging population and increasing use of organ transplant and immunosuppressive medications, subsets of patients are now more susceptible to skin cancer. Mohs micrographic surgery (MMS) has become the standard of care for the treatment of high-risk nonmelanoma skin cancers and is increasingly used to treat melanoma.

Dermabrasion in our practice.

Dermabrasion is a technique of facial resurfacing that allows the physician to sculpt the skin surface by surgically abrading, or planing the contours of the skin. User technique, device settings, and the combination of dermabrasion with other skin resurfacing treatments enable the physician to treat a wide variety of skin defects.

Acne scarring: current treatment options.

Acne vulgaris is one of the most common skin disorders treated in dermatology. Subsequent scarring that may result from acne can lead to devastating consequences. There are currently a wide variety of treatment modalities available for acne scarring.

A cosmetic approach to cutaneous defects.

The options available to cosmetic surgeons for the treatment of the aging face are expanding at a rapid pace. Although any one modality may help, often a combination of approaches provides the most dramatic results. Whereas some of these techniques represent refinements of old tools, others represent entirely new modalities (Box 1).