Publications by authors named "Christopher Au-Yeung"
Objective: Antiretrovirals do not prevent anal intraepithelial neoplasia. However, the influence of antiretrovirals in the natural history of invasive anal cancer is less clear. The objective is to investigate the impact of antiretrovirals in the time to the development of anal cancer in HIV-positive MSM.
View Article and Find Full Text PDFObjective: To estimate the lost investment of domestically educated doctors migrating from sub-Saharan African countries to Australia, Canada, the United Kingdom, and the United States.
Design: Human capital cost analysis using publicly accessible data.
Settings: Sub-Saharan African countries.
Background: HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission.
View Article and Find Full Text PDFArticle Synopsis
- Tuberculosis (TB) significantly contributes to mortality among individuals co-infected with HIV, especially in regions like Africa where the death rate is notably high.
- The study analyzed TB mortality rates in both HIV-positive and HIV-negative individuals across 212 countries from 2006 to 2008, revealing that African countries have TB/HIV death rates that are 29.9 times higher than those in non-African countries.
- Increased government health spending was linked to a substantial decrease in TB/HIV mortality rates, highlighting the need for better healthcare investments and universal access to antiretroviral therapy (HAART) to alleviate this public health crisis.
Objective: To examine if there is a significant difference in survival between elderly (>50 years) and nonelderly adult patients receiving combination antiretroviral therapy in Uganda between 2004 and 2010.
Design: Prospective observational study.
Methods: Patients 18-49 years of age (nonelderly) and 50 years of age and older enrolled in the AIDS Support Organization Uganda HIV/AIDS national programme were assessed for time to all-cause mortality.
Background: In clinical and cohort research, mortality estimates are often derived from manual reports generated by physicians or electronic reports from vital event registries. We examined the rate of underreporting of deaths by manual methods as compared with electronic reports from a vital event registry.
Methods: The retrospective analyses included deaths among participants registered in an observational cohort who initiated highly-active antiretroviral therapy (HAART) between August 1, 1996 and June 30, 2006.