Publications by authors named "Christopher A Mays"
Synthetic nanomaterials have many unique chemical and physical properties, mainly due to their high specific surface area and quantum confinement effect. Specifically, titanium dioxide (TiO ) nanomaterial has high stability, anticorrosive, and photocatalytic properties. However, there are concerns over adverse biological effects resulting from bioeffects.
View Article and Find Full Text PDFAssessment of the link between in utero exposure to 2-aminoanthracene (2AA) and type-1 diabetes (T1D).
J Diabetes Metab Disord
January 2017
Background: A recent diabetes report revealed an increased incidence in diabetes including type 1-diabetes (T1D). The increase in the numbers of T1D incidences are thought to be related to environmental reasons such as the exposure to environmental chemicals including arylamine 2-aminoanthracene (2AA). T1D is an autoimmune disease of the pancreatic islet in which insulin-producing beta cells are destroyed by auto-reactive T-cells and monocytic cells.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates how exposure to the environmental contaminant 2-aminoanthracene (2AA) during pregnancy might increase the risk of type 2 diabetes in offspring by affecting adipose tissue function.
- - Pregnant rats were given diets with varying levels of 2AA, and their offspring were analyzed for diabetes-related gene expression, serum glucose levels, and other health markers.
- - Findings show that exposure to 2AA resulted in gene changes related to diabetes, higher blood sugar levels, and larger fat cells in treated offspring, suggesting a combined effect with a high-fat diet increases diabetes risk.