Publications by authors named "Christophe Pol Stove"
Article Synopsis
- Dried blood microsampling offers benefits for home-sampling and studies due to better analyte stability, but requires validation for unstable molecules like folates.
- The study focused on folate stability in dried blood microsamples, specifically the stability of the main folate form, 5-methyltetrahydrofolate, under various storage conditions including temperature, light exposure, humidity, and storage methods.
- Results indicated that while folate levels remained stable at -20 °C and 4 °C for two weeks, room temperature storage reduced stability significantly, with humidity negatively affecting certain folate types, which could be mitigated by using desiccants.
Background: Stimulated by the increased recognition of phosphatidylethanol (PEth) as sensitive direct marker of alcohol intake, the Ghent University's Laboratory of Toxicology and the National Institute of Criminalistics and Criminology combined their efforts to develop a quantitative method. To facilitate implementation the focus was on the use of a sampling technique which allows quick and easy blood collection, without the need of dedicated personnel at any place/any time. In the meantime the cooperation of the two labs should also allow to initiate a Belgian network of laboratories capable of quantifying PEth.
View Article and Find Full Text PDF