Publications by authors named "Christophe Heugas"
Emergence of Plasmodium vivax Resistance to Chloroquine in French Guiana.
Antimicrob Agents Chemother
November 2019
Article Synopsis
- Recent studies have shown chloroquine resistance in Brazil and Bolivia, prompting a retrospective analysis of its effectiveness in French Guiana between 2009 and 2015 at Cayenne Hospital.
- Out of 172 patients studied, 164 responded well to treatment, resulting in a therapeutic efficacy of 95.3%, with only 8 treatment failures identified, including cases of true resistance and low drug concentrations.
- The study concludes that while current levels of resistance do not necessitate changes in treatment guidelines, increased use of primaquine is recommended to curb resistance, and the development of molecular markers for monitoring is essential.